McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-β superfamily member. Nature. 1997;387:83–90.
Article
CAS
PubMed
Google Scholar
Zimmers TA, Davies MV, Koniaris LG, Haynes P, Esquela AF, Tomkinson KN, McPherron AC, Wolfman NM, Lee SJ. Induction of cachexia in mice by systemically administered myostatin. Science. 2002;296:1486–8.
Article
CAS
PubMed
Google Scholar
Schuelke M, Wagner KR, Stolz LE, Hubner C, Riebel T, Komen W, Braun T, Tobin JF, Lee S-J. Myostatin mutation associated with gross muscle hypertrophy in a child. N Engl J Med. 2004;350:2682–8.
Article
CAS
PubMed
Google Scholar
Diel P, Schiffer T, Geisler S, Hertrampf T, Mosler S, Schulz S, Wintgens KF, Adler M. Analysis of the effects of androgens and training on myostatin propeptide and follistatin concentrations in blood and skeletal muscle using highly sensitive Immuno PCR. Mol Cell Endocrinol. 2010;330:1–9.
Article
CAS
PubMed
Google Scholar
Adams GR, Haddad F, Bodell PW, Tran PD, Baldwin KM. Combined isometric, concentric, and eccentric resistance exercise prevents unloading-induced muscle atrophy in rats. J Appl Physiol. 2007;103:1644–54.
Article
CAS
PubMed
Google Scholar
Roth SM, Martel GF, Ferrell RE, Metter EJ, Hurley BF, Rogers MA. Myostatin gene expression is reduced in humans with heavy-resistance strength training: a brief communication. Exp Biol Med. 2003;228:706–9.
CAS
Google Scholar
Walker KS, Kambadur R, Sharma M, Smith HK. Resistance training alters plasma myostatin but not IGF-1 in healthy men. Med Sci Sports Exerc. 2004;36:787–93.
Article
CAS
PubMed
Google Scholar
Adams GR, McCue SA. Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats. J Appl Physiol. 1998;84:1716–22.
CAS
PubMed
Google Scholar
Rommel C, Bodine SC, Clarke BA, Rossman R, Nunez L, Stitt TN, Yancopoulos GD, Glass DJ. Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol. 2001;3:1009–13.
Article
CAS
PubMed
Google Scholar
Shyu KG, Ko WH, Yang WS, Wang BW, Kuan P. Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes. Cardiovasc Res. 2005;68:405–14.
Article
CAS
PubMed
Google Scholar
Liu W, Thomas SG, Asa SL, Gonzalez-Cadavid N, Bhasin S, Ezzat S. Myostatin is a skeletal muscle target of growth hormone anabolic action. J Clin Endocrinol Metabol. 2003;88:5490–6.
Article
CAS
Google Scholar
Han DS, Chen YM, Lin SY, Chang HH, Huang DM, Chi YC, Yang WS. Serum myostatin levels and grip strength in normal subjects and patients on maintenance hemodialysis. Clin Endocrinol (Oxf). 2011;75:857–63.
Article
CAS
Google Scholar
Azzazy HME, Mansour MMH, Christenson RH. Doping in the recombinant era: strategies and counterstrategies. Clin Biochem. 2005;38:959–65.
Article
CAS
PubMed
Google Scholar
Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. J Cell Biol. 2002;157:137–48.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bogdanovich S, Krag TOB, Barton ER, Morris LD, Whittemore LA, Ahima RS, Khurana TS. Functional improvement of dystrophic muscle by myostatin blockage. Nature. 2002;420:418–21.
Article
CAS
PubMed
Google Scholar
Chang K-V, Hung C-Y, Li C-M, Lin Y-H, Wang T-G, Tsai K-S, Han D-S. Reduced flexibility associated with metabolic syndrome in community-dwelling elders. PLoS One. 2015;10:e0117167.
Article
PubMed
PubMed Central
Google Scholar
Chien M-Y, Huang T-Y, Wu Y-T. Prevalence of sarcopenia estimated using a bioelectrical impedance analysis prediction equation in community-dwelling elderly people in Taiwan. J Am Geriatr Soc. 2008;56:1710–5.
Article
PubMed
Google Scholar
Sallis J. Seven-Day physical activity recall. Med Sci Sports Exerc. 1997;29:89–103.
Google Scholar
Sallis JF, Haskell WL, Wood PD, Fortmann SP, Rogers T, BlairLAIR SN, Paffenbarger RS. Physical activity assessment methodology in the five-city project. Am J Epidemiol. 1985;121:91–106.
CAS
PubMed
Google Scholar
Wintgens KF, Dschietzig T, Stoeva S, Paulsson M, Armbruster FP. Plasma myostatin measured by a competitive ELISA using a highly specific antiserum. Clin Chim Acta. 2012;413:1288–94.
Article
CAS
PubMed
Google Scholar
Ju C-R, Chen R-C. Serum myostatin levels and skeletal muscle wasting in chronic obstructive pulmonary disease. Respir Med. 2011;106:102–8.
Article
PubMed
Google Scholar
Zamora E, Simó R, Lupón J, Galán A, Urrutia A, González B, Mas† D, Valle V. Serum myostatin levels in chronic heart failure. Rev Esp Cardiol (Engl Version). 2010;63:992–6.
Article
Google Scholar
Lakshman KM, Bhasin S, Corcoran C, Collins-Racie LA, Tchistiakova L, Forlow SB, Ledger K, Burczynski ME, Dorner AJ, LaVallie ER. Measurement of myostatin concentrations in human serum: circulating concentrations in young and older men and effects of testosterone administration. Mol Cell Endocrinol. 2009;302:26–32.
Article
CAS
PubMed
Google Scholar
Feldman BJ, Streeper RS, Farese RV, Yamamoto KR. Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects. Proc Natl Acad Sci U S A Biol Sci. 2006;103:15675–80.
Article
CAS
Google Scholar
Kim HS, Liang L, Dean RG, Hausman DB, Hartzell DL, Baile CA. Inhibition of preadipocyte differentiation by myostatin treatment in 3 T3-L1 cultures. Biochem Biophys Res Commun. 2001;281:902–6.
Article
CAS
PubMed
Google Scholar
Ehehalt S, Schweizer R, Blumenstock G, Pfaff C, Schurr N, Weber K, Ranke MB, Binder G. Investigation of myostatin serum levels before and after a 6-month lifestyle intervention program in obese children. Exp Clin Endocrinol Diabetes. 2011;119:238–42.
Article
CAS
PubMed
Google Scholar
Bhatt SP, Nigam P, Misra A, Guleria R, Luthra K, Jain SK, Qadar Pasha MA. Association of the myostatin gene with obesity, abdominal obesity and Low lean body mass and in Non-diabetic Asian Indians in north India. PLoS One. 2012;7:e40977.
Article
CAS
PubMed
PubMed Central
Google Scholar
Han D-S, Chu-Su Y, Chiang C-K, Tseng F-Y, Tseng P-H, Chen C-L, Wu K-D, Yang W-S. Serum myostatin is reduced in individuals with metabolic syndrome. PLoS One. 2014;9:e108230.
Article
PubMed
PubMed Central
Google Scholar
Hill J, Davies MV, Pearson AA, Wang JH, Hewick RM, Wolfman NW, Qiu Y. The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum. J Biol Chem. 2002;277:40735–41.
Article
CAS
PubMed
Google Scholar
Matsakas A, Bozzo C, Cacciani N, Caliaro F, Reggiani C, Mascarello F, Patruno M. Effect of swimming on myostatin expression in white and red gastrocnemius muscle and in cardiac muscle of rats. Exp Physiol. 2006;91:983–94.
Article
CAS
PubMed
Google Scholar
Sharma M, Kambadur R, Matthews KG, Somers WG, Devlin GP, Conaglen JV, Fowke PJ, Bass JJ. Myostatin, a transforming growth factor-?superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct. J Cell Physiol. 1999;180:1–9.
Article
CAS
PubMed
Google Scholar
Mahmoudabady M, Mathieu M, Dewachter L, Hadad I, Ray L, Jespers P, Brimioulle S, Naeije R, McEntee K. Activin-a, transforming growth factor-[beta], and myostatin signaling pathway in experimental dilated cardiomyopathy. J Card Fail. 2008;14:703–9.
Article
CAS
PubMed
Google Scholar
Hoenig MR. Hypothesis: myostatin is a mediator of cardiac cachexia. Int J Cardiol. 2008;124:131–3.
Article
PubMed
Google Scholar
Peters D, Barash IA, Burdi M, Yuan PS, Mathew L, Fridén J, Lieber RL. Asynchronous functional, cellular and transcriptional changes after a bout of eccentric exercise in the rat. J Physiol. 2003;553:947–57.
Article
CAS
PubMed
PubMed Central
Google Scholar
Holt RIG, Erotokritou-Mulligan I, McHugh C, Bassett EE, Bartlett C, Fityan A, Bacon JL, Cowan DA, Sönksen PH. The GH-2004 project: the response of IGF1 and type III pro-collagen to the administration of exogenous GH in non-Caucasian amateur athletes. Eur J Endocrinol. 2010;163:45–54.
Article
CAS
PubMed
Google Scholar
Tentori L, Graziani G. Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk? Pharmacol Res. 2007;55:359–69.
Article
CAS
PubMed
Google Scholar
Neuhouser ML, Di C, Tinker LF, Thomson C, Sternfeld B, Mossavar-Rahmani Y, Stefanick ML, Sims S, Curb JD, Lamonte M, Seguin R, Johnson KC, Prentice RL. Physical activity assessment: biomarkers and self-report of activity-related energy expenditure in the WHI. Am J Epidemiol. 2013;177:576–85.
Article
PubMed
PubMed Central
Google Scholar
Ainsworth BE, Haskell WL, Herrmann SD, Meckes N, Bassett DRJ, Tudor-Locke C, Greer JL, Vezina J, Whitt-Glover MC, Leon AS. 2011 compendium of physical activities: a second update of codes and MET values. In: Medicine & science in sports & exercise. 2011. p. 1575–81.
Google Scholar