References | Study Design | Population characteristics | Intervention | Supplement situation | Experimental design | Physiological Results | Performance results |
---|---|---|---|---|---|---|---|
[33] | Randomized double-blind crossover | 12 M: elite BMX cyclists, age: 19.2 ± 3.4 y, height: 174.2 ± 5.3 cm and BM: 72.4 ± 8.4 kg | 0.3 g•kg− 1 BM of NaHCO3 or 0.045 g•kg−1 BM of NaCI (PLA) | Ingested 90 min before the trial in gelatin capsules once | 3 races of BMX (track length of 400 m) with 15 min interval | ↑HCO3−, ↑pH and ↑BE vs. PLA, (12.95 ± 1.3, 7.2 ± 0.05 and − 12.66 ± 3.13 vs. 11.45 ± 1.3, 7.14 ± 0.05 and − 16.27 ± 3.18), =BLa, =HR, =RPE, =VO2, =VCO2 and = VE vs. PLA | =Time, = Velocity peak (VP) and = Time to VP vs. PLA |
[29] | Double-blind counterbalanced crossover | 18 M: rugby, judo (n = 2) and jiu-jitsu (n = 5), age: 26 ± 5 y; BM: 88.8 ± 6.8 kg; height: 1.78 ± 0.07 m; | 500 mg/kg BM of CL or NaHCO3 or CACO3 (PLA) Divided into four individual doses of 125 mg/kg BM | Last one within 4 h before trial, ingested in gelatin capsules for 5 consecutive days | 4 bouts of the upper body WAnT with 3 min interval | =HCO3−, =pH, =BE, =BLa vs. other conditions | ↑ TWM (2.9%) and ↑ 3rd + 4th of Wingate (5.9%) vs. CL and PLA =1st + 2nd of Wingate |
[39] | Randomized crossover | 10 M: age: 22 ± 4 y, height: 1.77 ± 0.06 m, BM: 76 ± 9 kg. | 0.5 g•kg− 1 BM of NaHCO3 or 0.2 g•kg− 1 BM of NaCI (PLA) Divided into 3 doses | Each dose at 4 h interval on experimental day, ingested as NR once | 2 WAnT with 5 min interval | ↑HCO3−,↑pH and ↑BE vs. PLA (12.7 ± 1.3, 7.22 ± 0.04 and − 13.7 ± 1.8 vs. 9.5 ± 1.7, 7.15 ± 0.05 and − 17.8 ± 2.1), =BLa vs PLA | ↑ Work completed (5 ± 4%) vs. PLA, = Rate of fatigue vs. PLA =PP (↓PLA, −8 ± 8%) |
[28] | Randomized double-blind crossover | 13 M: elite swimmers, age: 20.5 ± 1.4 y, BM: 80.1 ± 8.1 kg, height: 188 ± 8 cm | 0.3 g•kg− 1 BM of NaHCO3 or CACO3 (PLA) | Ingested 60 min before the trial in gelatin capsules once | Two 100 m freestyle sprints with 12 min interval | ↑HCO3−, ↑pH and ↑BE vs. PLA (10.61 ± 3.43, 7.15 ± 0.05 and − 18.68 ± 2.91 vs. 7.77 ± 2.41, 7.05 ± 0.06 and − 22.78 ± 2.21), =BLa vs. PLA | = 1st 100 m swim vs. PLA, ↓ Time of 2nd 100 m swim vs. PLA (1.5 s) |
[40] a | Randomized, double-blind, counterbalanced | 12 M: resistance-trained participants (age: 20.3 ± 2 y, BM:88.3 ± 13.2 kg, height:1.80 ± 0.07 m) | 0.3 g•kg− 1 BM of NaHCO3 or CACO3 (PLA) Divided into 4 equal doses | Each dose consumed at 10 min intervals, 1st dose at 80 min before the trial, ingested in gelatin capsules once | 4 sets of SQ, LP and KE with 120 s interval, 10-12RM per set with 90s interval | ↑HCO3−, ↑pH, ↑BE and ↑BLa vs. PLA (17.86 ± 3.63, 7.35 ± 0.04, − 7.67 ± 4.16 and 17.16 ± 2.09 vs. 14.19 ± 2.62, 7.09 ± 0.03, − 11.5 ± 3.2 and 12.49 ± 2.45) | ↑ Total volume (SQ + LP + KE + PT) vs. PLA (163.7 ± 15.1 vs. 156.7 ± 14.5) |
[41] | Double-blind, counterbalanced | 21 M, age: 25 ± 5 y, BM: 80.7 ± 10.6 kg, height: 1.79 ± 0.06 m | 0.3 g•kg− 1 of BM NaHCO3 or maltodextrin (PLA) | Ingested 0.2 g•kg− 1 BM alongside the breakfast, 0.1 g•kg− 1 BM 2 h before the trial in gelatin capsules once | A habituation trial of the cycle-capacity test to exhaustion at 110% of Wmax | ↑HCO3−, ↑pH, ↑BE and ↑BLa vs. PLA (15.26 ± 2.78, 7.28 ± 0.05, − 9.6 ± 3.38 and 14.5 ± 2.9 vs. 12.82 ± 2.1, 7.23 ± 0.06, − 12.69 ± 2.8 and 12.4 ± 2) | =TWD, except participants who have GI ↑TWD vs. PLA (48.4 ± 9.3 vs. 46.9 ± 9.2) |
[42]a | Randomized double-blind counterbalanced crossover | 20 rowers: age: 23 ± 4 y, height: 1.85 ± 0.08 m, BM: 82.5 ± 8.9 kg, | 0.3 g•kg− 1 BM of NaHCO3 or maltodextrin (PLA) | Ingested 0.2 g•kg− 1 BM 4 h before and 0.1 g•kg− 1 BM 2 h before the trial as NR once | 2000 m rowing-ergometer TTs | ↑HCO3−, ↑pH, ↑BE and ↑BLa vs. PLA (10.56 ± 1.75, 7.18 ± 0.06, − 15.56 ± 2.69 and 16,5 ± 0.9 vs. 9.1 ± 1.71, 7.12 ± 0.07, − 18.13 ± 2.77 and 14.1 ± 0.9) | = Time of 1st and 2nd 500 m, ↓ Time of 3rd and 4th 500 m (0.5 ± 1.2 s and 1.1 ± 1.7 s) |
[43] | Randomized, single-blind, counterbalanced | 14 swimmers (6 M, hight:181.2 ± 7.2 cm; BM: 80.3 ± 11.9 kg, 8F, height: 168.8 ± 5.6 cm; BM: 75.3 ± 10.1 kg) | 0.3 g•kg− 1 BM of NaHCO3 or 0.045 g•kg− 1 BM of NaCI (PLA) | Ingested 2.5 h before the trial as NR once | Completed 8x25m front crawl maximal effort sprints with 5 s interval | ↑HCO3−, ↑pH, ↑BE and ↑BLa vs. PLA (16 ± 0.05, 7.26 ± 0.01, − 11.1 ± 0.08 and 17.69 ± 1.06 vs. 13.8 ± 0.6, 7.2 ± 0.02, − 14.6 ± 1.1 and 14.62 ± 1.25), ↓K+ vs PLA (3.8 ± 0.1 vs. 4.4 ± 0.1), =NA+ | ↓Total swim time (2%) vs. PLA |
[32] | Randomized, double-blind, counterbalance crossover | 10 elite BMX riders, age: 20.7 ± 1.4 y, height: 178.3 ± 2.1 cm and BM: 77.9 ± 2.1 kg, | 0.3 g•kg− 1 BM of NaHCO3 or placebo (PLA) | Ingested 90 min before the trial in gelatin capsules once | 3x30s Wingate tests with 15 min interval | ↑HCO3−, ↑pH and ↑BE vs. PLA (10.17 ± 1.77, 7.22 ± 0.09 and 16.57 ± 3.51 vs. 6.88 ± 2.78, 7.09 ± 0.03 and − 22.49 ± 1.39), =BLa vs. PLA | =PP, = Time to PP, =Mean power, =Fatigue index vs. PLA |
[31] | Randomized double-blind counterbalanced | 11 trained cyclists (10 M and 1F), age: 24.5 ± 2.8 y, height: 1.78 ± 2.7 m and BM: 73.2 ± 3.8 kg | 0.3 g•kg− 1 BM of NaHCO3 or 0.2 g•kg− 1 BM of CaCO3 (PLA) | Ingested 90 min before the trial in gelatin capsules once | 70s supramaximal exercise | ↑HCO3−, ↑pH and ↑BE vs. PLA (19.53 ± 3.98, 7.3 ± 0.03 and − 6.15 ± 3.91 vs. 15.12 ± 3.15, 7.21 ± 0.07 and − 12.67 ± 3.81), =BLa, =VO2, =VCO2, =VE, =PO2, ↑PCO2 vs. PLA (42 ± 2.99 vs. 38.9 ± 3.65) | ↑P50 and ↑Ptot vs. PLA (469.6 ± 28.6 and 564.5 ± 29.5 vs. 448.2 ± 7.7 and 549.5 ± 29.1), =P20 and = Fatigue index vs. PLA |
[44] | Randomized double-blind crossover | 11 M trained cyclists, age: 32 ± 7.2 y; BM: 77.0 ± 9.2 kg | 0.3 g•kg− 1 BM of NaHCO3 or 0.21 g•kg− 1 BM of NaCI (PLA) | Ingested 70-40 min before trial (depending on individual time to peak pH) as NR once | 3 min all-out critical power test | =HCO3−, =H+, =BLa, =PO2 and = PCO2 vs. PLA | ↑TWD (5.5%) and ↑W′ (14%) vs. PLA, =CP vs. PLA |