Table 4 PICOS (Participants, Intervention, Comparison, Outcomes and Study design)

Participants

Healthy exercise adults

Intervention

Supplementation with NaHCO₃

Comparison

Same conditions with placebo or control group

Outcomes

Changes in some parameters that can express changes in energy metabolism (i.e., HCO₃⁻, pH, BE, BLa, VO₂, CO₂, PO₂ and PCO₂)

Study design

Crossover or counterbalanced double- or single-blind, randomized controlled trials