Fig. 8

Protein phosphorylation. Mammalian target of rapamycin (mTOR) (a), ribosomal protein S6 kinase beta-1 (p70S6K) (b), eukaryotic translation initiation factor 4E (EIF4E) (c), tumor protein p53 (p53) (d), p38 mitogen-activated protein kinases (p38MAPK) (e). Western blots representing the time-course effects are presented below the graphs. Based on the applied molecular standards, approximated molecular weights are indicated to the right. n = 9 for all timepoints. Values are normalized to PRE 90ss and are expressed as means ± SD; P < 0.05. * Significantly different from BL. # Significant difference between trials