Variables | Group | Pre-Intervention | Post-Intervention | Effect size | p-value | Mean difference (%) | CI −95% | CI + 95% |
---|---|---|---|---|---|---|---|---|
25(OH)rest [ng/ml] | EXP | 34.9 ± 4.7 | 40.3 ± 4.9* | 0.69 / Moderate | 0.02 | −3.9 (− 10.7%) | −7.03 | − 0.72 |
CON | 33.9 ± 4.8 | 31.8 ± 4.2 | 0.46 / Small | 0.13 | 2.1 (6.2%) | −0.68 | 4.88 | |
25(OH)max [ng/ml] | EXP | 36.5 ± 3.3 | 44.9 ± 4.9 | 1.64 / Large | < 0.001 | −7.7 (−20.9%) | − 11.14 | −4.30 |
CON | 34.7 ± 8.1 | 39.2 ± 7.6 | 0.57 / Small | 0.13 | −4.5 (−13.0%) | −10.57 | 1.55 | |
25(OH)D1 h [ng/ml] | EXP | 40.0 ± 8.8** | 45.5 ± 4.7* | 0.52 / Small | 0.22 | −3.9 (−9.4%) | − 10.44 | 2.70 |
CON | 33.3 ± 3.4 | 38.5 ± 9.7 | 0.71 / Moderate | 0.04 | −5.2 (−15.6%) | −10.11 | −0.29 | |
25(OH)D24h [ng/ml] | EXP | 36.2 ± 6.2* | 41.2 ± 5.0* | 0.76 / Moderate | 0.04 | −4.6 (−12.5%) | −9.00 | −0.14 |
CON | 30.0 ± 6.4 | 35.7 ± 6.9 | 0.87 / Moderate | 0.02 | −5.8 (− 19.4%) | −10.63 | −0.99 | |
TN rest [ng/ml] | EXP | 2.9 ± 1.9** | 2.0 ± 1.6* | 0.77 / Moderate | 0.12 | 1.7 (45.3%) | −0.51 | 3.82 |
CON | 7.2 ± 2.0 | 5.6 ± 4.2 | 0.61 / Moderate | 0.20 | 3.0 (35.2%) | −1.82 | 7.85 | |
TN max [ng/ml] | EXP | 5.1 ± 1.7*** | 2.7 ± 1.6*** | 1.44 / Large | 0.004 | 2.4 (47.4%) | 0.94 | 3.94 |
CON | 8.9 ± 6.3 | 5.3 ± 4.1 | 1.38 / Large | 0.02 | 7.6 (59.3%) | 1.73 | 13.56 | |
TN 1 h [ng/ml] | EXP | 4.9 ± 2.0 | 2.9 ± 2.0 | 0.98 / Moderate | 0.03 | 2.0 (40.8%) | 0.18 | 3.84 |
CON | 4.4 ± 3.2 | 4.7 ± 2.4 | 0.09 / Trivial | 0.82 | −0.3 (− 5.8%) | −2.63 | 2.12 | |
TN 24 h [ng/ml] | EXP | 6.3 ± 3.7 | 3.7 ± 1.2 | 0.82 / Moderate | 0.08 | 2.6 (40.7%) | −0.33 | 5.47 |
CON | 4.7 ± 1.2 | 3.1 ± 1.2 | 0.47 / Small | 0.28 | 1.6 (33.5%) | −1.49 | 4.65 | |
MB rest [ng/ml] | EXP | 44.7 ± 23.1 | 40.6 ± 17.6 | 0.19 / Trivial | 0.71 | 4.1 (9.2%) | −19.36 | 27.58 |
CON | 44.4 ± 11.8 | 37.1 ± 21.8 | 0.39 / Small | 0.43 | 7.2 (16.3%) | −12.11 | 26.54 | |
MB max [ng/ml] | EXP | 73.9 ± 32.0 | 58.7 ± 27.6 | 0.49 / Small | 0.16 | 15.2 (20.6%) | −7.12 | 37.52 |
CON | 93.4 ± 33.1 | 73.5 ± 43.7 | 0.49 / Small | 0.29 | 19.9 (21.3%) | −19.84 | 59.67 | |
MB 1 h [ng/ml] | EXP | 173.6 ± 104.5 | 92.6 ± 48.9 | 0.96 / Moderate | 0.01 | 81.5 (47.0%) | 24.69 | 138.35 |
CON | 102.6 ± 59.5 | 83.9 ± 50.0 | 0.32 / Small | 0.47 | 18.6 (18.2%) | −36.60 | 73.82 | |
MB 24 h [ng/ml] | EXP | 93.2 ± 56.2 | 59.5 ± 37.8 | 0.67 / Moderate | 0.15 | 33.7 (36.2%) | −14.17 | 81.60 |
CON | 98.3 ± 26.7 | 93.0 ± 50.7 | 0.13 / Trivial | 0.72 | 5.3 (5.4%) | −26.31 | 37.01 | |
CK rest [U/l] | EXP | 151.0 ± 59.5* | 166.4 ± 100.0 | 0.19 / Trivial | 0.58 | −15.4 (− 10.2%) | −75.57 | 44.72 |
CON | 234.2 ± 88.9 | 248.4 ± 179.0 | 0.1 / Trivial | 0.81 | −14.1 (−6.0%) | − 143.10 | 114.84 | |
CK max [U/l] | EXP | 226.1 ± 141.0 | 212.7 ± 112.0 | 0.1 / Trivial | 0.78 | 13.4 (5.9%) | −87.82 | 114.67 |
CON | 276.2 ± 118.2 | 286.6 ± 191.5 | 0.06 / Trivial | 0.87 | −10.4 (−3.8%) | − 152.70 | 131.84 | |
CK 1 h [U/l] | EXP | 248.0 ± 161.8 | 214.3 ± 109.0 | 0.23 / Small | 0.46 | 33.7 (13.6%) | −63.22 | 130.62 |
CON | 276.8 ± 122.3 | 213.2 ± 113.4 | 0.52 / Small | 0.16 | 63.5 (22.9%) | −29.34 | 156.39 | |
CK 24 h [U/l] | EXP | 361.3 ± 238.9 | 243.3 ± 91.5* | 0.55 / Small | 0.20 | 97.7 (28.1%) | −59.56 | 255.03 |
CON | 434.3 ± 143.9 | 332.0 ± 155.6 | 1.17 / Moderate | 0.05 | 143.1 (32.9%) | 64.74 | 221.49 | |
LDH rest [U/l] | EXP | 337.1 ± 73.5 | 333.1 ± 80.5 | 0.05 / Trivial | 0.82 | 4.0 (1.2%) | −34.60 | 42.60 |
CON | 339.4 ± 47.8 | 333.1 ± 60.1 | 0.11 / Trivial | 0.69 | 6.2 (1.8%) | −27.30 | 39.74 | |
LDH max [U/l] | EXP | 400.5 ± 108.0 | 395.9 ± 68.6 | 0.18 / Trivial | 0.54 | 17.5 (4.4%) | −44.25 | 79.36 |
CON | 401.4 ± 63.8 | 413.5 ± 79.6 | 0.16 / Trivial | 0.33 | −12.1 (−3.0%) | −38.25 | 14.04 | |
LDH 1 h [U/l] | EXP | 361.4 ± 87.8 | 354.2 ± 69.4 | 0.21 / Small | 0.37 | 18.3 (5.1%) | −25.25 | 61.88 |
CON | 355.0 ± 44.9 | 368.6 ± 72.2 | 0.22 / Small | 0.35 | −13.6 (−3.8%) | −43.99 | 16.86 | |
LDH 24 h [U/l] | EXP | 344.9 ± 75.5 | 313.5 ± 66.6 | 0.02 / Trivial | 0.94 | −1.8 (−0.5%) | −51.33 | 47.68 |
CON | 339.1 ± 56.8 | 321.1 ± 31.1 | 0.07 / Trivial | 0.74 | 4.1 (1.2%) | −21.87 | 29.99 | |
TNFα rest [pg/ml] | EXP | 9.7 ± 5.7 | 5.6 ± 2.6 | 0.88 / Moderate | 0.09 | 4.1 (42.2%) | −0.75 | 8.93 |
CON | 13.7 ± 7.4 | 12.5 ± 4.4 | 0.19 / Trivial | 0.65 | 1.2 (8.9%) | −4.52 | 6.96 | |
TNFα max [pg/ml] | EXP | 23.9 ± 15.2 | 10.5 ± 4.6 | 1.14 / Moderate | 0.01 | 13.4 (56.2%) | 3.48 | 23.40 |
CON | 22.9 ± 13.7 | 22.7 ± 17.4 | 0.01 / Trivial | 0.97 | 0.2 (0.8%) | −12.6 | 12.98 | |
TNF α 1 h [pg/ml] | EXP | 21.9 ± 16.8 | 8.4 ± 3.7 | 1.06 / Moderate | 0.03 | 13.5 (61.7%) | 1.74 | 25.26 |
CON | 18.7 ± 11.4 | 21.3 ± 12.2 | 0.21 / Small | 0.65 | −2.6 (−13.9%) | −14.91 | 9.69 | |
TNF α 24 h [pg/ml] | EXP | 19.8 ± 14.2 | 11.6 ± 5.7 | 0.73 / Moderate | 0.02 | 8.2 (41.6%) | 1.55 | 14.94 |
CON | 13.9 ± 6.7 | 13.7 ± 7.3 | 0.02 / Trivial | 0.95 | 0.1 (1.1%) | −5.56 | 5.87 | |
IL-6 rest [pg/ml] | EXP | 1.4 ± 1.3 | 1.9 ± 1.8 | 0.25 / Small | 0.23 | −0.3 (−18.7%) | −0.74 | 0.20 |
CON | 1.5 ± 1.3 | 2.1 ± 1.6 | 0.49 / Small | 0.10 | −0.6 (−44.1%) | −1.42 | 0.15 | |
IL-6 max [pg/ml] | EXP | 2.0 ± 1.9 | 1.7 ± 1.0 | 0.29 / Small | 0.39 | 0.33 (16.1%) | −0.49 | 1.15 |
CON | 2.7 ± 1.5 | 2.5 ± 2.3 | 0.01 / Trivial | 0.98 | −0.01 (− 0.4%) | −1.18 | 1.16 | |
IL-6 1 h [pg/ml] | EXP | 2.7 ± 2.3 | 2.3 ± 1.3 | 0.22 / Small | 0.59 | 0.39 (14.4%) | −1.14 | 1.92 |
CON | 3.1 ± 2.0 | 3.0 ± 2.0 | 0.02 / Trivial | 0.95 | −0.04 (−1.5%) | −1.40 | 1.32 | |
IL-6 24 h [pg/ml] | EXP | 1.8 ± 1.2 | 1.0 ± 0.9** | 0.72 / Moderate | 0.11 | 0.79 (43.5%) | −0.20 | 1.77 |
CON | 2.0 ± 1.2 | 2.4 ± 1.6 | 0.26 / Small | 0.46 | −0.3 (−14.9%) | −1.17 | 0.57 |