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Table 1 Comparison of Assay Methods Characterizing UC-II® Undenatured Type II Collagen

From: Letter to the editor UC-II® Undenatured type II collagen: update to analytical methods

UC-II® Study Design Research Material (Lot No.) Undenatured Type II Collagen (in 40-mg UC-II® material)
Per ELISA-Old Assay Per ELISA-New Assay
Efficacy study - healthy adults* 1109006 10.8 mg (27.0%) 2.3 mg (5.8%)
Efficacy study – people with osteoarthritis ** 1204004 10.8 mg (27.1%) 1.2 mg (3.0%)
Typical lot sold into commerce 1309029 10.6 mg (26.5%) 1.3 mg (3.3%)
  1. ELISA indicates enzyme-linked immunosorbent assay
  2. *Lugo et al. J Int Soc Sports Nutr. 2013;10:48
  3. **Lugo et al. Nutr J. 2016;15:14