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Table 2 Effects of chromium histidinate and biotin on body weight, Cr and biotin intake and serum parameters in exercise-trained rats

From: Biotin and chromium histidinate improve glucose metabolism and proteins expression levels of IRS-1, PPAR-γ, and NF-κB in exercise-trained rats

Parameters C CrHis Bio CrHis+Bio E E + CrHis E + Bio E + Bio + CrHis
Final body weight, g 312.29 ± 4.33a 301.86 ± 2.47a 307.00 ± 4.20a 301.43 ± 6.01a 282.29 ± 2.62b 270.86 ± 2.48b 276.71 ± 4.93b 273.29 ± 3.23b
Cr intake, μg/rat/day 23.52 ± 1.15d 32.45 ± 2.07b 24.64 ± 1.83c 32.43 ± 2.30b 25.76 ± 1.46c 35.4 ± 2.33a 26.88 ± 2.91c 36.88 ± 3.15a
Biotin intake, μg/rat/day 5.46 ± 0.82c 5.72 ± 0.75c 135.3 ± 4.26b 135.1 ± 3.85b 5.98 ± 0.68c 6.24 ± 1.33c 147.5 ± 6.55a 153.75 ± 8.70a
Glucose, mg/dL 121.50 ± 3.53a 110.71 ± 1.67b 118.67 ± 1.48b 106.86 ± 1.03c 112.29 ± 2.67b 97.71 ± 1.95d 109.29 ± 1.51b 93.57 ± 1.25e
Cholesterol, mg/dl 86.72 ± 3.23a 78.25 ± 2.61b 80.55 ± 3.42b 75.15 ± 3.20c 77.43 ± 1.95b 71.86 ± 2.35d 76.99 ± 2.83b 67.55 ± 2.85e
HDL, mg/dL 11.48 ± 0.44d 14.29 ± 0.42c 13.32 ± 0.42cd 15.86 ± 0.63c 15.29 ± 0.78c 18.14 ± 0.55b 16.14 ± 0.59c 22.71 ± 1.43a
Triglyceride, mg/dL 139.00 ± 9.84a 91.57 ± 4.85c 108.67 ± 5.74b 77.00 ± 5.23d 68.43 ± 3.05e 61.14 ± 2.82ef 65.71 ± 6.28e 51.71 ± 4.45g
AST, U/L 245.67 ± 44.12 240.71 ± 16.38 239.00 ± 20.12 237.29 ± 17.02 239.71 ± 15.48 243.71 ± 19.67 242.43 ± 11.29 236.43 ± 21.01
ALT, U/L 102.00 ± 3.39 100.71 ± 4.32 103.17 ± 7.12 104.57 ± 4.45 106.29 ± 5.36 103.14 ± 2.76 105.29 ± 4.55 103.29 ± 3.90
  1. Data are given as mean ± standard error. (a-g) The difference between the groups with different letters is statistically significant (p < 0.05). C Control, CrHis Chromium histidinate, Bio Biotin, E Exercise, HDL High-Density Lipoprotein, AST Aspartate aminotransferase, ALT Alanine aminotransferase