Study | Subjects | Design | Supplement Ingredients (Sorted by order listed on Supplement Facts label) | Timing | Training Protocol | Performance Testing Protocol | Results (d) | Ref # |
---|---|---|---|---|---|---|---|---|
Kraemer et al. 2007 | 9 resistance trained males | Double-blind, placebo controlled, cross-over, 7-day supplementation study | L-Arginine (2000 mg) D-Ribose (1500 mg) L-Carnitine (400 mg) L-Citrulline (200 mg) Betaine (100 mg) Caffeine (70 mg) | 30 min prior to exercise or at a similar time on off days | NA | CMVJ, six sets of BS RTF at 80% 1RM, isometric squat force1 | ↑ Power (NA) ↑ RTF for 5 of 6 sets (d = 0.41–1.08) | [49] |
Outlaw et al. 2014 | 20 resistance trained males | Double-blind, placebo controlled, training study | Prop. Blend: (8400 mg) Creatine β-alanine BCAAs (4800 mg) Caffeine (275 mg) | 30 min prior to exercise or during the morning hours on off days | 8 days of supplementation with four split body training sessions | DEXA, VJ, BP & LP 1RM, WAnT1 | ↔ Power ↔ Body Composition ↔ BP 1RM ↔ LP 1RM | [48] |
Collins et al. 2017 | 25 resistance trained males and females | Double-blind, placebo controlled, 7-day supplementation study | β-alanine (2100 mg) Arginine nitrate (1300 mg) Folic acid (325 mcg) Caffeine (200 mg) Niacin (65 mg) Vitamin B12 (45 mcg) | Unreported time point during supplementation phase | NA | BP and LP 1RM, 2 × 10 BP and LP at 70% 1RM, BP and LP RTF at 70% 1RM, 4 km cycle TT1 | ↔ Retention of force production ↔ Muscular endurance ↔ Lifting volume ↔ Power | [23] |
Martin et al. 2017 | 30 resistance trained males | Double-blind, placebo controlled, supplementation study | Creatine (2000 mg) Β-alanine (1600 mg) L-Citrulline (1000 mg) Caffeine (300 mg) L-Norvaline (200 mg) L-Theanine (100 mg) Whole coffee fruit extract (100 mg) Theacrine (50 mg) | Unreported time point during supplementation phase | NA | Leg extension RTF at 30% or 80% 1RM1 | ↔ RTF ↔ Volume load | [50] |