|
Variable
|
Baseline
|
Supplementation (week)
|
|---|
|
4
|
8
|
|---|
|
Body Mass (kg)
|
|
Placebo
|
81.60 ± 3.0
|
82.10 ± 3.04
|
82.30 ± 2.96
|
|
CIT-malate
|
79.20 ± 2.50
|
79.50 ± 2.52
|
80.10 ± 2.42
|
|
GSH + CIT
|
73.60 ± 1.74*
|
74.60 ± 1.69
|
74.60 ± 1.73*
|
|
Lean Mass (kg)
|
|
Placebo
|
59.92 ± 10.42
|
59.93 ± 10.33
|
59.81 ± 9.81
|
|
CIT-malate
|
59.43 ± 8.47
|
59.59 ± 8.46
|
59.84 ± 7.93
|
|
GSH + CIT
|
55.70 ± 7.28
|
56.46 ± 6.91*
|
56.20 ± 6.93
|
|
Fat Mass (kg)
|
|
Placebo
|
13.10 ± 1.17
|
13.70 ± 1.19
|
14.00 ± 1.20
|
|
CIT-malate
|
11.20 ± 1.04
|
11.50 ± 0.92
|
11.90 ± 0.96
|
|
GSH + CIT
|
9.90 ± 0.71
|
10.30 ± 0.71
|
10.60 ± 0.69*
|
|
Total Body Water (kg)
|
|
Placebo
|
48.20 ± 1.31
|
48.20 ± 1.32
|
48.40 ± 1.28
|
|
CIT-malate
|
47.90 ± 1.14
|
48.10 ± 1.16
|
48.40 ± 1.14
|
|
GSH + CIT
|
45.00 ± 0.89
|
45.50 ± 0.89
|
45.60 ± 0.89
|
|
Δ Lean Mass (kg)
|
|
Placebo
| |
0.01 ± −0.09
|
−0.11 ± 0.61
|
|
CIT-malate
| |
0.16 ± − 0.01
|
0.41 ± − 0.54
|
|
GSH + CIT
| |
0.76 ± − 0.37
|
0.5 ± − 0.35
|
|
Δ Total Body Water (kg)
|
|
Placebo
| |
0.0 ± 0.01
|
0.2 ± 0.03
|
|
CIT-malate
| |
0.2 ± 0.02
|
0.3 ± 0.0
|
|
GSH + CIT
| |
0.5 ± 0.0
|
0.6 ± 0.0
|
|
Net Δ LM-TBW (kg)
|
|
Placebo
| |
0.01 ± − 0.10
|
−0.79 ± 0.58
|
|
CIT-malate
| |
0.04 ± 0.08
|
0.11 ± − 0.54
|
|
GSH + CIT
| |
0.26 ± 0.37
|
0.10 ± − 0.35
|
- Mean ± SEM, *Significantly different from Placebo (p < 0.05), Δ = change from baseline, Net Δ = difference in the change in lean mass and total body water from baseline, LM lean mass, TBW total body water
