| CON | EX-30 | EX-60 | p-value |
---|---|---|---|---|
IL-1ra | Â | Â | Â | Â |
 Fasting (pg/mL) | 193.8 ± 135.4 | 202.2 ± 117.7 | 186.4 ± 98.5 | 0.95 |
 Peak (pg/mL) | 260.8 ± 183.2 | 300.0 ± 212.6 | 375.5 ± 359.9 | 0.26 |
 Time to peak (hours) | 4.1 ± 3.5 | 3.8 ± 3.0 | 2.3 ± 2.6 | 0.34 |
IL-4 | Â | Â | Â | Â |
 Fasting (pg/mL) | 97.9 ± 75.5 | 89.3 ± 50.3 | 98.8 ± 68.0 | 0.63 |
 Peak (pg/mL) | 126.2 ± 95.9 | 118.2 ± 66.4 | 158.3 ± 132.7 | 0.65 |
 Time to peak (hours) | 3.0 ± 3.4 | 2.5 ± 2.5 | 2.1 ± 2.6 | 0.23 |
IL-5 | Â | Â | Â | Â |
 Fasting (pg/mL) | 2.6 ± 1.0 | 2.5 ± 0.7 | 2.8 ± 0.8 | 0.72 |
 Peak (pg/mL) | 2.9 ± 1.0 | 2.8 ± 0.8 | 3.2 ± 1.1 | 0.23 |
 Time to peak (hours) | 1.8 ± 2.0 | 3.9 ± 3.1 | 3.6 ± 3.5 | 0.18 |
IL-6 | Â | Â | Â | Â |
 Fasting (pg/mL) | 34.7 ± 50.4 | 30.8 ± 45.8 | 28.8 ± 29.7 | 0.92 |
 Peak (pg/mL) | 35.5 ± 47.9 | 47.7 ± 68.7 | 44.1 ± 50.3 | 0.73 |
 Time to peak (hours) | 1.6 ± 2.8 | 2.5 ± 3.0 | 1.8 ± 2.7 | 0.63 |
IL-10 | Â | Â | Â | Â |
 Fasting (pg/mL) | 77.1 ± 48.5 | 64.2 ± 37.7 | 67.9 ± 35.1 | 0.30 |
 Peak (pg/mL) | 98.4 ± 48.3 | 79.6 ± 36.9 | 96.7 ± 57.0 | 0.23 |
 Time to peak (hours) | 2.7 ± 3.1 | 4.2 ± 3.1 | 2.8 ± 2.9 | 0.50 |
TNF-α |  |  |  |  |
 Fasting (pg/mL) | 9.1 ± 6.6 | 10.1 ± 8.9 | 9.7 ± 5.7 | 0.47 |
 Peak (pg/mL) | 10.9 ± 6.4 | 12.8 ± 12.6 | 12.4 ± 8.2 | 0.72 |
 Time to peak (hours) | 2.7 ± 3.0 | 2.3 ± 2.6 | 1.8 ± 2.6 | 0.49 |