Thirty-four healthy men and women were randomly assigned to two groups: 1) a soybean oil placebo (PL) or 2) a multi-ingredient dietary supplement (DS) containing 99 mg of caffeine and a propriety blend containing 1510 mg of CLA, green tea extract (45% EGCG), L-leucine, L-isoleucine and L-valine. Twenty-two participants completed the study (PL: n=11; age, 34 + 12 years; body mass, 97.0 + 22.6 kg; BMI, 34.1 ± 6.1; DS n=11; age, 36+ 11.1 years; body mass, 91.9 + 18.7 kg; BMI, 30.0 + 4.9). Both groups consumed two pills with breakfast and two pills with lunch. Body composition and android fat (dual-energy X-ray absorptiometry), waist and hip circumferences, blood pressure and heart rate were measured at baseline and after 8 weeks of supplementation. Participants were instructed to maintain normal dietary and exercise habits for the duration of the study. Data was analyzed using JMP 9 Pro (Cary, NC), significance was set to p<0.05. A two-way ANOVA with repeated measurements was used to evaluate changes in dependent variables over time ([Pre x Post] x [PL x DS]). If significant time, group, or group-by-time interactions were reported, a Tukey test was used for post hoc comparisons.