The mean value of glutathione concentration (GSH) of Group II had increased significantly from 101.21 ± 46.41 mg/dl to 196.89 ± 35.11 mg/dl (t = 1.943, p ≤ 0.05) while that of Group I had decreased from 86.16 to 81.94 mg/dl (p > 0.05). The mean levels of glutathione peroxidase of Group II had increased significantly from 23.75 ± 9.01 μ/gHb to 41.03 ± 5.58 μ/gHb (t = 5.857, p ≤ 0.05) while the same had decreased significantly in Group I from 18.37 to 15.11 μ/gHb. The levels of TBARS (which is a measure of lipid peroxidation) had decreased significantly in Group II from 0.367 ± 0.111 to 0.197 ± 0.227 nmol/ml (t = 2.015, p ≤ 0.05) and in Group I from 0.446 ± 0.14 to 0.38 ± 0.152 nmol/ml (t = 1.139, p > 0.05). The distance covered in 12 minutes by the athletes of Group II increased significantly from 2305 ± 365.2m to 2734 ± 602.7m (t = 2.163, p ≤ 0.05), whereas the same had decreased in Group I from 2150.4 ± 471.5m to 2106.4 ± 365.2 m (p > 0.05) after the study period. The number of steps taken by Group II increased significantly from 31.91 ± 4.69 to 33.92 ± 4.57 (t = 5.057, p ≤ 0.05) while it had decreased in Group I. This indicates the efficiency of antioxidant defense system provided by the intake of tomato juice containing lycopene.