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Table 5 (A,B,C,D) - Changes in blood and urine parameters (R1,R2,R3,R4) in subjects without EAH, n = 50

From: The prevalence of exercise-associated hyponatremia in 24-hour ultra-mountain bikers, 24-hour ultra-runners and multi-stage ultra-mountain bikers in the Czech Republic

A

Pre-race

Parameter

R1

R2

R3

R4

Haematocrit (%)

41.7 (3.7)

41.8 (3.0)

42.1 (3.2)

41.7 (2.3)

Plasma sodium (mmol/l)

138.0 (2.7)

137.7 (2.1)

140.0 (1.7)

141.8 (1.9)

Plasma potassium (mmol/l)

6.5 (1.5)

4.6 (0.3)

6.6 (0.9)

5.1 (0.4)

Plasma osmolality (mosmol/kg H 2 O)

289.9 (5.0)

289.4 (4.7)

288.6 (3.4)

288.7 (3.4)

Urine specific gravity (g/ml)

1.015 (0.004)

1.016 (0.004)

1.013 (0.005)

1.015 (0.007)

Urine osmolality (mosmol/kg H 2 O)

485.01 (219.1)

530.01 (272.3)

364.8 (163.3)

444.4 (273.0)

Urine potassium (mmol/l)

28.3 (28.9)

50.4 (37.7)

28.3 (15.8)

37.0 (28.9)

Urine sodium (mmol/l)

58.7 (46.1)

82.8 (40.8)

81.3 (39.5)

94.2 (52.3)

K/Na ratio in urine

0.5 (0.4)

0.6 (0.4)

0.4 (0.2)

0.5 (0.4)

Transtubular potassium gradient

6.9 (6.7)

25.7 (28.9)

7.0 (7.0)

15.5 (22.1)

Glomerular filtration rate (ml/min)

86.9 (15.0)

82.9 (8.6)

93.0 (7.6)

86.9 (8.2)

B

Post-race

Parameter

R1

R2

R3

R4

Haematocrit (%)

42.8 (3.0)

40.8 (2.8)

40.8 (2.9)

39.7 (2.9)

Plasma sodium (mmol/l)

137.4 (2.6)

136.8 (2.8)

138.7 (2.5)

139.2 (2.5)

Plasma potassium (mmol/l)

6.1 (1.0)

4.6 (0.9)

5.0 (0.6)

5.1 (0.5)

Plasma osmolality (mosmol/kg H 2 O)

292.7 (4.2)

291.8 (5.0)

290.4 (6.0)

290.1 (4.4)

Urine specific gravity (g/ml)

1.021 (0.004)

1.022 (0.004)

1.019 (0.010)

1.025 (0.007)

Urine osmolality (mosmol/kg H 2 O)

764.3 (196.9)

730.9 (241.4)

505.0 (312.0)

763.4 (291.4)

Urine potassium (mmol/l)

77.8 (25.4)

61.9 (47.9)

44.2 (27.8)

76.3 (31.2)

Urine sodium (mmol/l)

43.2 (30.6)

44.4 (44.9)

51.2 (34.7)

80.4 (58.9)

K/Na ratio in urine

2.3 (1.0)

2.3 (2.7)

0.9 (0.6)

2.2 (3.0)

Transtubular potassium gradient

35.6 (19.7)

40.3 (41.4)

20.5 (17.7)

42.8 (22.6)

Glomerular filtration rate (ml/min)

69.6 (12.4)

71.2 (9.9)

86.2 (9.5)

72.3 (12.2)

C

Change (absolute)

Parameter

R1

R2

R3

R4

Haematocrit (%)

1.1 (3.2)

–1.0 (2.6)

–1.3 (2.0)*

–2.0 (2.2)

Plasma sodium (mmol/l)

–0.6 (3.9)

–0.9 (2.8)

–1.3 (2.6)

–2.6 (2.4)**

Plasma potassium (mmol/l)

–0.4 (1.7)

–0.1 (1.0)

–1.6 (1.1)**

–0.0 (0.5)

Plasma osmolality (mosmol/kg H 2 O)

2.8 (4.2)

2.4 (6.2)

1.8 (5.8)

1.4 (5.5)

Urine specific gravity (g/ml)

0.006 (0.004)**

0.006 (0.006)**

0.006 (0.011)

0.010 (0.009)**

Urine osmolality (mosmol/kg H 2 O)

279.3 (195.1)**

200.8 (342.4)*

114.2 (355.8)**

319.0 (326.9)**

Urine potassium (mmol/l)

49.5 (39.0)**

11.5 (22.9)

15.9 (35.9)

39.3 (40.6)**

Urine sodium (mmol/l)

–15.6 (37.5)

–37.8 (46.0)**

–30.1 (38.4)*

–13.8 (70.3)

K/Na ratio in urine

1.7 (0.7)**

1.7 (2.4)*

0.56 (0.7)*

1.7 (3.1)

Transtubular potassium gradient

28.7 (14.1)**

14.6 (46.4)

13.5 (20.0)*

27.3 (23.7)**

Glomerular filtration rate (ml/min)

–17.2 (14.7)**

–11.7 (9.8)**

–6.8 (6.1)**

–14.6 (14.2)**

D

Change (%)

Parameter

R1

R2

R3

R4

Haematocrit (%)

2.8 (8.0)

–2.4 (6.1)

–3.1 (4.8)*

–4.8 (5.1)

Plasma sodium (mmol/l)

–0.4 (2.8)

–0.6 (2.0)

–0.9 (1.9)

–1.8 (1.7)**

Plasma potassium (mmol/l)

–6.3 (27.8)

–0.6 (22.9)

–24.6 (14.1)**

–1.0 (9.2)

Plasma osmolality (mosmol/kg H 2 O)

0.9 (1.5)

0.8 (2.1)

0.6 (2.0)

0.5 (1.9)

Urine specific gravity (g/ml)

0.7 (0.4)**

0.5 (0.6)**

0.6 (1.1)

1.0 (0.9)**

Urine osmolality (mosmol/kg H 2 O)

57.6 (85.3)**

37.9 (161.2)*

38.4 (195.6)**

71.8 (185.1)**

Urine potassium (mmol/l)

174.8 (458.2)**

22.9 (22.0)

56.3 (191.8)

106.2 (422.9)**

Urine sodium (mmol/l)

–26.5 (81.6)

–46.0 (118.1)**

–37.0 (36.1)*

–14.6 (105.2)

K/Na ratio in urine

359.9 (187.2)**

281.7 (327.6)*

148.7 (222.3)*

366.6 (347.9)

Transtubular potassium gradient

417.7 (575.1)**

56.9 (1185.7)

192.7 (2133.5)*

176.6 (1196.2)**

Glomerular filtration rate (ml/min)

–19.8 (14.7)**

–14.1 (11.7)**

–7.3 (6.7)**

–16.8 (13.9)**

  1. Results are presented as mean (SD), *= p ≤ 0.05, **= p < 0.01.