Skip to main content

Table 3 Kidney function parameters before (Pre) and after 12 weeks (Post) of either creatine or placebo supplementation in resistance-trained individuals consuming a high-protein diet

From: Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein diet?

 

Creatine (n = 12)

Placebo (n = 14)

 

Variable

Pre

Post

Pre

Post

P (group x time interaction)

Albuminuria (mg/24 h)

19 (38)

15 (28)

8 (7)

4 (2)

0.99

Proteinuria (g/24 h)

0.14 (0.11)

0.14 (0.10)

0.10 (0.05)

0.10 (0.07)

0.83

Urinary potassium (mEq/24 h)

65 (24)

59 (22)

68 (24)

65 (19)

0.86

Urinary sodium (mEq/24 h)

231 (56)

226 (91)

195 (65)

191 (52)

0.99

Serum potassium (mEq/L)

4 (0.3)

4 (0.4)

5 (0.4)

4 (0.4)

0.26

Serum sodium (mEq/L)

141 (3)

141 (2)

142 (3)

141 (4)

0.53

Serum creatinine (mg/dL)

1.1 (0.1)

1.2 (0.2)

1.0 (0.1)

1.1 (0.1)

0.30

Serum urea (mg/dL)

41.7 (10.7)

39.2 (11.7)

33.3 (6.7)

33.4 (7.2)

0.63

  1. Data expressed as mean (standard deviation). There were no significant differences between groups at baseline. No significant within- or between-group differences were noted. Note: Conversion factors for units: serum creatinine in mg/dL to mol/L, ×88.4; serum urea in mg/dL to mmol/L, ×0.166; glomerular filtration rate in mL/min/1.73 m2 to mL/s/1.73 m2, ×0.01667.