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Table 4 Metabolic variables of METABO and placebo groups from week 0 through week 8

From: Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women

Blood lipid   METABO   Placebo P
   n = 27   n = 18 Value1
  Baseline Mid point End of study % Baseline Mid point End of study %  
  (Week 0) (Week 4) (Week 8) Change (Week 0) (Week 4) (Week 8) Change  
Cholesterol, (mg/dL) 178.33 ± 26.49 NP 173.30 ± 30.25 -2.8 175.78 ± 31.45 NP 176.50 ± 31.14 0.4 0.3
HDL (mg/dL) 48.44 ± 12.47 NP 48.56 ± 15.26 0.2 50.28 ± 10.86 NP 48.94 ± 12.06 -2.7 0.49
LDL (mg/dL) 103.96 ± 26.04 NP 103.00 ± 30.92 -0.9 100.94 ± 28.53 NP 100.78 ± 30.17 -0.1 0.88
Cholesterol: HDL Ratio 3.91 ± 1.15 NP 3.85 ± 1.24 -1.5 3.67 ± 1.16 NP 3.87 ± 1.44 1.2 0.15
TAG (mg/dL) 118.44 ± 40.42 NP 99.59 ± 44.77 -15.9 120.22 ± 67.45 NP 117.06 ± 63.39 -2.6 0.07
Glucose (mg/dL) 89.81 ± 8.04 NP 92.67 ± 7.74 3.2 90.56 ± 8.3 NP 94.56 ± 13.82 4.4 0.60
Adiponectin (pg/mL) 10.20 ± 0.81 10.16 ± 0.74 9.93 ± 0.76 -0.2 10.17 ± 8.80 10.05 ± 0.80 10.04 ± 0.83 -0.3 0.47, 0.15
Resistin (pg/mL) 82.74 ± 38.47 81.65 ± 36.72 69.63 ± 26.04 -15.8 86.77 ± 50.18 68.38 ± 32.11 81.57 ± 46.75 -5.9 0.08, 0.26
Leptin (pg/mL) 8.99 ± 0.88 8.93 ± 0.94 8.729 ± 1.25 -3.0 8.85 ± 1.09 8.36 ± 1.07 8.76 ± 1.25 -3.0 0.03*, 0.5
lL-6 (pg/mL) 0.45 ±0.83 0.37 ± 0.56 0.34 ± 0.94 -24.5 0.45 ± 1.22 0.38 ± 0.82 0.38 ± 1.44 -14.8 0.97, 0.89
TNF-α (pg/mL) 1.71 ± 1.16 1.45 ± 1.04 1.58 ± 1.08 -7.6 1.35 ± 1.82 1.53 ± 1.67 1.19 ± 1.25 -11.7 0.41, 0.49
  1. Values are mean ± SD.
  2. 1P values are for the differences between the two groups, METABO versus placebo at week 4 and week 8, respectively. No significant differences between the week 8 time points were noted using ANCOVA (where the week 0 time points were used as the covariate). * Significant difference at the week 4 mid time point for Leptin using ANCOVA. NP: not performed; HDL: high density lipoprotein; LDL: low density lipoprotein; TAG: triacylglycerols; IL-6: interleukin-6; TNF-α: tumor necrosis factor-α.