| |
Males
|
Females
|
|---|
|
Discovery cohort
|
Replication cohort
|
Discovery cohort
|
Replication cohort
|
|---|
|
Total
|
13,834 (49.9)
|
20,763 (30.8)
|
13,901 (50.1)
|
46,749 (69.2)
|
|
Age (years)
|
48.8 ± 11.2
|
50.8 ± 11.3
|
48.8 ± 11.1
|
50.3 ± 10.5
|
|
BMI (kg/m2)
|
25.2 ± 3.5
|
25.4 ± 3.5
|
23.5 ± 3.7
|
23.6 ± 3.7
|
|
Drinking
|
1714 (12.4)
|
2740 (13.2)
|
246 (1.8)
|
841 (1.8)
|
|
Smoking
|
2886 (20.9)
|
4351 (21.0)
|
397 (2.9)
|
1334 (2.9)
|
|
Educational attainment
|
5.7 ± 0.9
|
5.7 ± 0.9
|
5.3 ± 1.0
|
5.3 ± 1.0
|
|
TG (mg/dL)
|
133.8 ± 104.5
|
140.3 ± 127.8
|
99.4 ± 68.6
|
103.4 ± 73.8
|
|
TG > 150 mg/dL
|
3951 (28.6)
|
6151 (29.6)
|
1916 (13.8)
|
7434 (15.9)
|
|
LDL-C (mg/dL)
|
122.3 ± 31.4
|
121.0 ± 31.3
|
119.4 ± 31.9
|
120.6 ± 31.8
|
|
LDL-C > 130 mg/dL
|
5295 (38.3)
|
7555 (36.4)
|
4676 (33.6)
|
16,488 (35.3)
|
|
HDL-C (mg/dL)
|
47.9 ± 11.0
|
47.8 ± 11.1
|
58.0 ± 13.1
|
58.1 ± 13.2
|
|
HDL-C < 40 mg/dL (males)
|
3137 (22.7)
|
4815 (23.2)
|
–
|
–
|
|
HDL-C < 50 mg/dL (females)
|
–
|
–
|
3837 (27.6)
|
12,980 (27.8)
|
|
TG/HDL-C
|
3.2 ± 3.4
|
3.3 ± 4.4
|
1.9 ± 1.9
|
2.0 ± 2.1
|
|
TG/HDL-C > 3.75 (males) a
|
3572 (25.8)
|
5622 (27.1)
|
–
|
–
|
|
TG/HDL-C > 3 (females) a
|
–
|
–
|
2093 (15.1)
|
7856 (16.8)
|
- Data are shown in n (%) or mean ± SD
- aCombining TG and HDL-C, the undesirable range for TG/HDL-C is > 3.75 (= 150/40, for male) or > 3 (= 150/50, for female)
