Table 1 Basic characteristics of the 95,247 Taiwan Biobank subjects
Males | Females | |||
|---|---|---|---|---|
Discovery cohort | Replication cohort | Discovery cohort | Replication cohort | |
Total | 13,834 (49.9) | 20,763 (30.8) | 13,901 (50.1) | 46,749 (69.2) |
Age (years) | 48.8 ± 11.2 | 50.8 ± 11.3 | 48.8 ± 11.1 | 50.3 ± 10.5 |
BMI (kg/m2) | 25.2 ± 3.5 | 25.4 ± 3.5 | 23.5 ± 3.7 | 23.6 ± 3.7 |
Drinking | 1714 (12.4) | 2740 (13.2) | 246 (1.8) | 841 (1.8) |
Smoking | 2886 (20.9) | 4351 (21.0) | 397 (2.9) | 1334 (2.9) |
Educational attainment | 5.7 ± 0.9 | 5.7 ± 0.9 | 5.3 ± 1.0 | 5.3 ± 1.0 |
TG (mg/dL) | 133.8 ± 104.5 | 140.3 ± 127.8 | 99.4 ± 68.6 | 103.4 ± 73.8 |
TG > 150 mg/dL | 3951 (28.6) | 6151 (29.6) | 1916 (13.8) | 7434 (15.9) |
LDL-C (mg/dL) | 122.3 ± 31.4 | 121.0 ± 31.3 | 119.4 ± 31.9 | 120.6 ± 31.8 |
LDL-C > 130 mg/dL | 5295 (38.3) | 7555 (36.4) | 4676 (33.6) | 16,488 (35.3) |
HDL-C (mg/dL) | 47.9 ± 11.0 | 47.8 ± 11.1 | 58.0 ± 13.1 | 58.1 ± 13.2 |
HDL-C < 40 mg/dL (males) | 3137 (22.7) | 4815 (23.2) | – | – |
HDL-C < 50 mg/dL (females) | – | – | 3837 (27.6) | 12,980 (27.8) |
TG/HDL-C | 3.2 ± 3.4 | 3.3 ± 4.4 | 1.9 ± 1.9 | 2.0 ± 2.1 |
TG/HDL-C > 3.75 (males) a | 3572 (25.8) | 5622 (27.1) | – | – |
TG/HDL-C > 3 (females) a | – | – | 2093 (15.1) | 7856 (16.8) |