Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis and mechanical power in rats

Table 2 Human equivalent doses (HEDs) used to feed the different groups of animals in the chronic study

Conversion of the human dose to rat dose	Daily rat dose (mg/kg BW)	HED (mg/kg BW)^a	HED (mg/day)
Control group (CTL)	–	–	–
Rhodiola group (Rho)	21.8	4.17	250
Rhaponticum group (Rha)	21.8	4.17	250
Rhaponticum/Rhodiola 50–50 group (Rha + Rho)	43.5	8.33	500

^a Formula from FDA, 2005; Human equivalent dose (HED; mg/kg) = animal dose in mg/kg x (animal weight in kg/human weight in kg)^0.33. BW body weight

ISSN: 1550-2783