Table 1 Human equivalent doses (HEDs) administered to the different groups of animals in the acute study
Conversion of human dose to rat dose | Daily rat dose (mg/kg body weight) | HED (mg/kg)a | HED (mg/day) |
|---|---|---|---|
Control group (CTL) | – | – | – |
Rhodiola group (Rho) | 43.5 | 8.33 | 500 |
Rhaponticum group (Rha) | 43.5 | 8.33 | 500 |
Rhaponticum/Rhodiola 50–50 dose 1 group (Rha + Rho D1) | 87.1 | 16.67 | 1000 |
Rhaponticum/Rhodiola 50–50 dose 2 group (Rha + Rho D2) | 43.5 | 8.33 | 500 |
Rhaponticum/Rhodiola 50–50 dose 3 group (Rha + Rho D3) | 21.8 | 4.17 | 250 |
Rhaponticum/Rhodiola 50–50 dose 4 group (Rha + Rho D4) | 8.7 | 1.67 | 100 |