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Table 5 Investigations examining the effects of caffeine mouth rinsing (CMR) on exercise performance

From: International society of sports nutrition position stand: caffeine and exercise performance

Author

Participants

Protocol

Results

Doering et al. 2014 [69]

Well-trained cyclists (n = 10)

• 10 s rinse 35 mg caffeine/25 mL X 8

• Placebo rinse

⬌ plasma caffeine levels

⬌ cycling TT Performance

De Pauw et al. 2015 [70]

Healthy males (n = 10)

• 20 s- 25 mL Rinse 1.2% caffeine

• 20 s- 25 mL Rinse 6.4% CHO

• Placebo Rinse

*↑ stroop task performance

Pomportes et al. 2017 [71]

Physically active males (n = 16) and females (n = 6)

• 20 s- 25 mL rinse 67 mg caffeine

• 20 s- 25 mL rinse 7.0% CHO

• 20 s- 25 mL rinse 0.4 g guarana

• Placebo rinse

⬌ variability or production durations

⬌ errors made

Beaven et al. 2013 [72]

Recreationally active males (n = 12)

• 5 s- 25 mL rinse 1.2% caffeine

• 5 s- 25 mL rinse 6% CHO

• Placebo rinse

*↑ mean power in first sprint for caffeine and CHO rinses

NS ↑ maximal power in first two sprints

Beaven et al. 2013 [72]

Recreationally active males (n = 12)

• 5 s- 25 mL rinse 1.2% caffeine

• 5 s- 25 mL rinse 6.0% CHO

• 5 s- 25 mL rinse 1.2% caffeine

+ 6.0% CHO

*↑ peak power in first sprint

*↑ mean power in fifth sprint

Kizzi et al. 2016 [73]

Glycogen depleted, recreationally active males (n = 8)

• 10 s- 25 mL rinse 2.0% caffeine

• Placebo rinse

⬌ mean and peak power in 4th and 5th sprint

Sinclair and Bottoms 2014 [74]

Healthy males (n = 12)

• 5 s- 25 mL rinse 0.032% caffeine

• 5 s- 25 mL rinse 6.4% CHO

• Placebo rinse

*↑ arm crank TT performance

Bottoms et al. 2014 [74]

Healthy males (n = 12)

• 5 s- 125 mL rinse w/ 32 mg of caffeine

• 5 s – 6.4% CHO solution

• Placebo rinse

*↑ distance cycled during the caffeine mouth rinse trial (16.2 ± 2.8 km) was significantly greater compared to placebo trial (14.9 ± 2.6 km).

There was no difference between CHO and caffeine trials

Pataky et al. 2016 [75]

Recreationally trained male (n = 25) and female (n = 13) cyclists

• Placebo rinse + 6 mg/kg caffeine capsule

• 25 mL rinse 300 mg caffeine + placebo capsule

• 25 mL rinse 300 mg caffeine + 6 mg/kg caffeine capsule

*↑ 3 km cycling TT performance

Lesniak et al. 2016 [76]

Recreationally active females (n = 7)

• 5 s- 25 mL rinse 1.2% caffeine

• 5 s- 25 mL rinse 6.0% CHO

• 5 s- 25 mL rinse 1.2% caffeine

+ 6% CHO

⬌ cycling TT performance

Dolan et al. 2017 [77]

College lacrosse players (n = 10)

• 5 s- 25 mL Rinse 1.2% caffeine

• 5 s- 25 mL Rinse 6.0% CHO

• 5 s- 25 mL Rinse 1.2% caffeine

+ 6.0% CHO

• Placebo rinse

• No rinse

⬌ intermittent sport performance

Clarke et al. 2015 [78]

Recreationally resistance-trained males (n = 15)

• 5 s- 25 mL rinse 1.2% caffeine

• 5 s- 25 mL rinse 6.0% CHO

• 5 s- 25 mL rinse 1.2% caffeine

+ 6.0% CHO

• Placebo rinse

⬌ total weight lifted

  1. Bold text associated with reported trial outcomes; s = seconds, mL = milliliters, CHO = carbohydrate, TT time trial, * = significant difference, NS = non-significant difference, ↑ = improved performance, ↓ = decreased, ⬌ = no improvement/change, mg = milligrams