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Table 2 Baseline measurements of the included randomized controlled trials

From: Effects of vitamin D3 supplementation on serum 25(OH)D concentration and strength in athletes: a systematic review and meta-analysis of randomized controlled trials

Reference

Analyzed (n = 149)

VD3 Daily Dosage IU

Males (%)

Mean Age Years

25(OH)D (ng/mL)

25(OH)D (nmol/L)

25(OH)D Method of Analysis

Lost to Follow-up

Jung 2018 [30]

20

5000

60% (21/35)

20.1 ± 0.15

10.9 ± 0.47

27.3 ± 1.18

CLIA analyzer (Liaison XL, Dasorin, Italy)

9

15

PL

  

12.36 ± 0.78

30.9 ± 1.95

(20.45%)

Fairbairn 2018 [31]

28

3570

100

21.5 ± 2.8

37.2 ± 7.6

93 ± 19

LC-MS/MS at Canterbury Health

Laboratories, Christchurch, New Zealand

0

29

PL

 

20.9 ± 2.8

38 ± 6.8

95 ± 17

 

Close 2013b [32]

5

5000

100

18 ± 5

11.6 ± 10

29 ± 25

HPLC-MRM (Becton Dickinson, Oxford, UK)

0

5

PL

  

21.2 ± 11.6

53 ± 29

 

Close 2013a [28]

6

5714

100

21 ± 1

20.4 ± 10.4

51 ± 26

HPLC-MRM (Becton Dickinson, Oxford, UK)

5

10

2857

 

22 ± 2

21.2 ± 10.4

53 ± 26

(16.70%)

9

PL

 

21 ± 1

20.8 ± 10.8

52 ± 27

 

Wyon 2016 [29]

11

18,750

100

29 ± 10.6

13.2 ± 3.8

32.8 ± 9.4

ECLIA (Tecan Infinite F500, Mannedorf, Switzerland)

0

11

PL

 

26 ± 7.4

16.3 ± 2.7

40.7 ± 6.8

 
  1. Data are mean ± standard deviation unless stated otherwise. CLIA Chemiluminescent immunoassay, ECLIA Electrochemiluminescent immunoassay, HPLC-MRM High-performance liquid chromatography tandem multiple reaction mode, HPLC-MS High-performance liquid chromatography-tandem mass spectrometry, LC–MS/MS Liquid chromatography mass spectrometry, PL Placebo. 2013a, 30 football and rugby athletes were recruited in reference 28; 2013b, 10 soccer players were recruited in reference [32]