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Table 3 Mean (± standard deviation) Blood Hematocrit, and Serum Bicarbonate (HCO3), pH, Sodium (Na+), and Lactate

From: The effects of a novel bicarbonate loading protocol on serum bicarbonate concentration: a randomized controlled trial

 

Placebo

AcuteSB

ModSB

 

Baseline

Post-ingestion

Baseline

Post-ingestion

p-value

Baseline

Post-ingestion

p-value

Effect size (Hedges’g)

HCO3 (mmol·L−1)

27.1 (±2.3)

29.8 (±1.4)

27.7 (±1.3)

33.5 (±2.0)

< 0.01

27.1 (±2.2)

34.7 (±2.2)

< 0.01

0.53

pH

7.60 (±.04)

7.64 (±.05)

7.56 (±.06)

7.67 (±.08)

0.04

7.58 (±.05)

7.67 (±.04)

< 0.01

−0.18

Na+ (mmol·L−1)

138.8 (±1.3)

137.2 (±1.0)

139.7 (±2.3)

140.3 (±1.8)

0.10

138.8 (±1.3)

140.0 (±1.5)

0.06

0.32

Hematocrit (%)

45.9 (±3.5)

46.5 (±2.8)

46.8 (±2.2)

45.0 (±2.9)

0.03

46.2 (±3.5)

43.4 (±1.7)

< 0.01

−0.57

Lactate (mmol·L−1)

1.6 (±0.7)

1.7 (±0.2)

1.6 (±0.1)

2.0 (±0.3)

NS

1.4

(±0.2)

1.9 (±0.5)

NS

0.21

  1. p-value indicates significantly different change from baseline compared to placebo (p ≤ 0.05)
  2. Effect size reflects the difference in baseline to post-ingestion change between AcuteSB and ModSB
  3. Significantly higher than AcuteSB (p ≤ 0.05)
  4. AcuteSB: Acute sodium bicarbonate ingestion trial
  5. ModSB: Modified sodium bicarbonate ingestion trial
  6. NS: No significant interaction effect