Skip to main content

Advertisement

Table 3 Mean (± standard deviation) Blood Hematocrit, and Serum Bicarbonate (HCO3), pH, Sodium (Na+), and Lactate

From: The effects of a novel bicarbonate loading protocol on serum bicarbonate concentration: a randomized controlled trial

  Placebo AcuteSB ModSB  
Baseline Post-ingestion Baseline Post-ingestion p-value Baseline Post-ingestion p-value Effect size (Hedges’g)
HCO3 (mmol·L−1) 27.1 (±2.3) 29.8 (±1.4) 27.7 (±1.3) 33.5 (±2.0) < 0.01 27.1 (±2.2) 34.7 (±2.2) < 0.01 0.53
pH 7.60 (±.04) 7.64 (±.05) 7.56 (±.06) 7.67 (±.08) 0.04 7.58 (±.05) 7.67 (±.04) < 0.01 −0.18
Na+ (mmol·L−1) 138.8 (±1.3) 137.2 (±1.0) 139.7 (±2.3) 140.3 (±1.8) 0.10 138.8 (±1.3) 140.0 (±1.5) 0.06 0.32
Hematocrit (%) 45.9 (±3.5) 46.5 (±2.8) 46.8 (±2.2) 45.0 (±2.9) 0.03 46.2 (±3.5) 43.4 (±1.7) < 0.01 −0.57
Lactate (mmol·L−1) 1.6 (±0.7) 1.7 (±0.2) 1.6 (±0.1) 2.0 (±0.3) NS 1.4 (±0.2) 1.9 (±0.5) NS 0.21
  1. p-value indicates significantly different change from baseline compared to placebo (p ≤ 0.05)
  2. Effect size reflects the difference in baseline to post-ingestion change between AcuteSB and ModSB
  3. Significantly higher than AcuteSB (p ≤ 0.05)
  4. AcuteSB: Acute sodium bicarbonate ingestion trial
  5. ModSB: Modified sodium bicarbonate ingestion trial
  6. NS: No significant interaction effect