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Table 3 Circulating markers of muscle damage and inflammation in females ingesting ascorbic acid or placebo before exercise

From: Effects of ascorbic acid supplementation on oxidative stress markers in healthy women following a single bout of exercise

Test Placebo Ascorbic Acid (1000 mg)
Pre-exercise Post-exercise 30 min post-exercise Pre-exercise Post-exercise 30 min post-exercise
hsCRP, mg/L 0.68 ± 0.13 0.67 ± 0.13 0.62 ± 0.12 0.57 ± 0.12 0.63 ± 0.10 0.52 ± 0.11
LDH, U/L 126 ± 5.3 124 ± 5.0 129 ± 4.8 128 ± 4.5 130 ± 4.9 132 ± 5.6
Total CK, U/L 93.5 ± 8.1 111.9 ± 10.2a, p = 0.019 111.7 ± 10.2a, p = 0.004 92.4 ± 13.7 101.0 ± 14.1 109.3 ± 14.3a, p = 0.033
CK-MB, U/L 19.7 ± 2.8 22.6 ± 3.8 15.6 ± 2.8 18.4 ± 2.6 21.3 ± 2.8 15.1 ± 2.0
  1. The exercise bout was performed indoors on a stationary bicycle for 30 min at intensity corresponding to 65–75% of maximum heart rate. Values are means ± SE; n = 19 per cohort. The p-values indicate the results of a Bonferroni post-hoc analysis. acompared with pre-exercise value (within group). hsCRP, high-sensitivity C-reactive protein; LDH, lactate dehydrogenase; CK, creatine kinase; CK-MB, creatine kinase-muscle and brain isoenzyme