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Table 2 Cardiometabolic parameters in response to n-3 PUFA or placebo supplementation, in baseline and after 8 weeks (follow up)

From: Effects of n-3 fatty acids and exercise on oxidative stress parameters in type 2 diabetic: a randomized clinical trial

  n-3 PUFA (n = 15)   Placebo (n = 15)   
Baseline Follow-up Diff. Mean (95% CI) Baseline Follow-up Diff. Mean (95% CI) P value*
HbA1c (%) 6.11 ± 0.57 6.47 ± 0.86   7.01 ± 1.06 7.40 ± 1.72   
Log HbA1c (%)b 0.17 ± 0.01 0.16 ± 0.02 −0.008 (− 0.014 to − 0.002) 0.14 ± 0.02 0.14 ± 0.02 − 0.005 (− 0.020 to 0.010) 0.752
Glucose (mg/dl) 134.7 ± 10.1 131.1 ± 6.7 − 3.5 (− 0.01 to 4.7) 130.8 ± 5.5 122.8 ± 4.6 −8.0 (− 2.5 to 9.2) 0.382
Triglycerides (mg/dl) 136.5 ± 75.9 113.3 ± 71.4   152.9 ± 59.5 153 ± 56.4   
Log Triglycerides (mg/dl)b 0.009 ± 0.004 0.011 ± 0.005 0.002 (0.000 to 0.004)** 0.008 ± 0.003 0.008 ± 0.003 0.000 (− 0.001 to 0.001) 0.005
Total Cholesterol (mg/dl) 182.4 ± 41.3 177.1 ± 44.7 − 5.8 (− 17.8 to 6.1) 192.3 ± 38.2 193.3 ± 40.4 0.7 (− 15.8 to 17.2) 0.385
HDL-cholesterol (mg/dl) 49.7 ± 15.9 52 ± 15 2.3 (− 0.5 to 5.1) 51.7 ± 12.2 53.9 ± 12.7 2.1 (− 3.0 to 7.2) 0.904
LDL-cholesterol (mg/dl) 105.4 ± 35.3 102.4 ± 41.4 − 3.9 (− 16.4 to 8.6) 110.0 ± 35.6 108.8 ± 41.7 −1.4 (− 16.9 to 14.1) 0.732
Albuminuria (mg/dl) 9.67 ± 6.06 8.89 ± 7.04   5.64 ± 3.52 3.99 ± 2.25   
Log Albuminuria (mg/dl)a 2.25 ± 0.59 1.92 ± 0.49 − 0.33 (− 0.73 to 0.07) 2.91 ± 0.82 2.74 ± 1.04 − 0.16 (− 0.93 to 0.60) 0.426
  1. Values are presented as mean ± standard deviation. *Models were adjusted for age, gender, duration of diabetes and use of drugs, Logarithmic transformation, aSquare root transformation, bInverse transformation, **(p = 0.004 compared to before supplementation
  2. p value in bold was statiscally significant