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Table 2 Cardiometabolic parameters in response to n-3 PUFA or placebo supplementation, in baseline and after 8 weeks (follow up)

From: Effects of n-3 fatty acids and exercise on oxidative stress parameters in type 2 diabetic: a randomized clinical trial

 

n-3 PUFA (n = 15)

 

Placebo (n = 15)

  

Baseline

Follow-up

Diff. Mean (95% CI)

Baseline

Follow-up

Diff. Mean (95% CI)

P value*

HbA1c (%)

6.11 ± 0.57

6.47 ± 0.86

 

7.01 ± 1.06

7.40 ± 1.72

  

Log HbA1c (%)b

0.17 ± 0.01

0.16 ± 0.02

−0.008 (− 0.014 to − 0.002)

0.14 ± 0.02

0.14 ± 0.02

− 0.005 (− 0.020 to 0.010)

0.752

Glucose (mg/dl)

134.7 ± 10.1

131.1 ± 6.7

− 3.5 (− 0.01 to 4.7)

130.8 ± 5.5

122.8 ± 4.6

−8.0 (− 2.5 to 9.2)

0.382

Triglycerides (mg/dl)

136.5 ± 75.9

113.3 ± 71.4

 

152.9 ± 59.5

153 ± 56.4

  

Log Triglycerides (mg/dl)b

0.009 ± 0.004

0.011 ± 0.005

0.002 (0.000 to 0.004)**

0.008 ± 0.003

0.008 ± 0.003

0.000 (− 0.001 to 0.001)

0.005

Total Cholesterol (mg/dl)

182.4 ± 41.3

177.1 ± 44.7

− 5.8 (− 17.8 to 6.1)

192.3 ± 38.2

193.3 ± 40.4

0.7 (− 15.8 to 17.2)

0.385

HDL-cholesterol (mg/dl)

49.7 ± 15.9

52 ± 15

2.3 (− 0.5 to 5.1)

51.7 ± 12.2

53.9 ± 12.7

2.1 (− 3.0 to 7.2)

0.904

LDL-cholesterol (mg/dl)

105.4 ± 35.3

102.4 ± 41.4

− 3.9 (− 16.4 to 8.6)

110.0 ± 35.6

108.8 ± 41.7

−1.4 (− 16.9 to 14.1)

0.732

Albuminuria (mg/dl)

9.67 ± 6.06

8.89 ± 7.04

 

5.64 ± 3.52

3.99 ± 2.25

  

Log Albuminuria (mg/dl)a

2.25 ± 0.59

1.92 ± 0.49

− 0.33 (− 0.73 to 0.07)

2.91 ± 0.82

2.74 ± 1.04

− 0.16 (− 0.93 to 0.60)

0.426

  1. Values are presented as mean ± standard deviation. *Models were adjusted for age, gender, duration of diabetes and use of drugs, Logarithmic transformation, aSquare root transformation, bInverse transformation, **(p = 0.004 compared to before supplementation
  2. p value in bold was statiscally significant