Enzymatically modified isoquercitrin supplementation intensifies plantaris muscle fiber hypertrophy in functionally overloaded mice

Table 3 Body and plantaris muscle weight in Study 1

	Sham	Sham + EMIQ	Ovld	Ovld + EMIQ		P value
	Sham	Sham + EMIQ	Ovld	Ovld + EMIQ	Ovld	EMIQ	Ovld × EMIQ
Food intake (g day⁻¹)	5.1 ± 0.2	5.2 ± 0.2	5.0 ± 0.2	5.0 ± 0.2	0.388	0.711	0.849
Initial body weight (g)	35.9 ± 0.5	35.5 ± 0.7	36.0 ± 0.5	35.0 ± 0.6	0.749	0.222	0.609
Final body weight (g)	39.3^a ± 0.6	39.7^a ± 0.7	38.1^b ± 0.9	37.6^b ± 0.6	0.032	0.964	0.547
Left Plantaris (mg)	21.6^a ± 1.0	22.7^a ± 0.9	43.4^b ± 2.3	46.0^b ± 3.2	0.000	0.388	0.727
Right Plantaris (mg)	21.8^a ± 0.9	23.3^a ± 0.8	41.5^b ± 3.0	45.3^b ± 3.7	0.000	0.298	0.638
Av. Plantaris (mg)	21.7^a ± 0.6	23.0^a ± 0.8	42.4^b ± 2.3	45.6^b ± 3.2	0.000	0.290	0.648
Plantaris/B.W. (%)	0.055^a ± 0.002	0.058^a ± 0.002	0.111^b ± 0.005	0.121^b ± 0.007	0.000	0.290	0.648

Values are mean ± SEM. Means without a common letter are statistically different (P < 0.05, two-way ANOVA (analysis of variance) followed by Tukey’s test). Sham: sham-operated mice, Sham + EMIQ: sham-operated mice receiving EMIQ, Ovld: functionally overloaded mice, Ovld + EMIQ: functionally overloaded mice receiving EMIQ

ISSN: 1550-2783