Variable | Group | Baseline | Pre-Run | 60-min Post | 24-hr Post | 48-hr Post | Group Mean | p-value (GG) | p-value (WSC) | RFT Covariate p-value (WSC) |
---|---|---|---|---|---|---|---|---|---|---|
Lymphocytes (K/uL) | P | 1.83 ± 0.58 | 2.50 ± 0.81 | 1.47 ± 0.54 | 2.04 ± 0.69 | 2.26 ± 0.35 | 2.02 ± 0.11 | G = 0.732 | G = 0.414 | |
TC | 1.82 ± 0.53 | 2.63 ± 0.72 | 1.43 ± 0.25 | 1.75 ± 0.45 | 2.18 ± 0.46 | 1.96 ± 0.14 | T <0.001* | T q   = 0.013* | T q   = 0.509 | |
Time Mean | 1.83 ± 0.11 | 2.56 ± 0.15†| 1.45 ± 0.09†Ψ | 1.90 ± 0.12Ψ◊ | 2.22 ± 0.08†Ψ◊# | G X T = 0.404 | G X T L   = 0.905 | G X T L   = 0.200 | ||
WBC (K/uL) | P | 5.93 ± 1.45 | 6.54 ± 1.71 | 12.61 ± 3.39^†Ψ | 6.64 ± 1.84◊ | 5.14 ± 0.84 | 7.37 ± 0.29 | G = 0.314 | G = 0.398 | |
TC | 5.83 ± 1.50 | 6.85 ± 1.61 | 10.80 ± 3.40†Ψ | 5.73 ± 1.20◊ | 5.33 ± 1.05 | 6.91 ± 0.35 | T <0.001* | T q   <0.001* | T L   = 0.613 | |
Time Mean | 5.88 ± 0.29 | 6.70 ± 0.33†| 11.71 ± 0.66†Ψ | 6.18 ± 0.32◊ | 5.24 ± 0.18†Ψ◊# | G X T = 0.223 | G X T q   = 0.162 | G X T q   = 0.500 | ||
MID (K/uL) | P | 0.45 ± 0.14 | 0.53 ± 0.20 | 0.67 ± 0.23†| 0.49 ± 0.19◊ | 1.10 ± 0.25†Ψ◊# | 0.65 ± 0.03 | G = 0.477 | G = 0.607 | |
TC | 0.43 ± 0.11 | 0.61 ± 0.19†| 0.54 ± 0.15 | 0.40 ± 0.10Ψ | 1.10 ± 0.32†Ψ◊# | 0.61 ± 0.04 | T <0.001* | T L   = 0.022* | T q   = 0.495 | |
Time Mean | 0.44 ± 0.03 | 0.57 ± 0.04†| 0.60 ± 0.04†| 0.44 ± 0.03Ψ◊ | 1.10 ± 0.06†Ψ◊# | G X T = 0.276 | G X T q   = 0.388 | G X T q   = 0.562 | ||
GRAN (K/uL) | P | 3.59 ± 1.07 | 3.53 ± 1.04 | 10.49 ± 3.49^†Ψ | 4.09 ± 1.28◊ | 1.76 ± 0.59†Ψ◊# | 4.69 ± 0.24 | G = 0.349 | G = 0.566 | |
TC | 3.59 ± 1.41 | 3.64 ± 0.86 | 8.83 ± 3.35†Ψ | 3.58 ± 0.98◊ | 2.05 ± 1.00◊ | 4.34 ± 0.29 | T < 0.001* | T q   <0.001* | T L   = 0.326 | |
Time Mean | 3.59 ± 0.24 | 3.58 ± 0.19 | 9.66 ± 0.67†Ψ | 3.84 ± 0.23◊ | 1.90 ± 0.15†Ψ◊# | G X T = 0.259 | G X T q   = 0.168 | G X T q   = 0.493 | ||
GM-CSF (pg/mL) | P | 26.38 ± 41.92 | 25.49 ± 31.29 | 26.08 ± 34.72 | 22.64 ± 30.21 | 22.41 ± 29.72 | 24.60 ± 9.15 | G = 0.485 | G = 0.696 | |
TC | 42.26 ± 47.28 | 37.37 ± 45.40 | 35.27 ± 46.54 | 29.52 ± 38.02 | 29.41 ± 36.03 | 34.77 ± 11.04 | T = 0.056§ | T L   = 0.022* | T q   = 0.794 | |
Time Mean | 34.32 ± 8.64 | 31.43 ± 7.36 | 30.68 ± 7.81 | 26.08 ± 6.57†Ψ◊ | 25.91 ± 6.34†Ψ◊ | G X T = 0.407 | G X T L   = 0.221 | G X T L   = 0.319 |