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Table 4 Assessment of blood chemistry changes denoting lipids, glucose, muscle and hepatorenal function concordant to supplementation

From: Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance

    Treatment  
    PLA CrM CrN-Low CrN-High Chi-Square
  Cholesterol No Change 0 0 0 0 0.33
   Normal Base; Exceed Day 7 10 8 12 13  
   Normal Base; Exceed Day 28 1 1 0 0  
   Normal Day7; Exceed Day 28 0 2 1 0  
  HDL-C No Change 6 9 10 10 0.72
   Normal Base; Exceed Day 7 2 1 0 0  
Lipids & glucose   Normal Base; Exceed Day 28 1 0 1 1  
  Normal Day7; Exceed Day 28 2 1 2 2  
LDL-C No Change 9 10 13 12 0.30
  Normal Base; Exceed Day 7 0 0 0 0  
  Normal Base; Exceed Day 28 2 1 0 0  
  Normal Day7; Exceed Day 28 0 0 0 1  
Triglycerides No Change 11 11 13 13 0.31
  Normal Base; Exceed Day7 0 0 0 0  
  Normal Base; Exceed Day28 0 0 0 0  
  Normal Day7; Exceed Day28 0 0 0 0  
  Glucose No Change 10 9 11 11 0.56
   Normal Base; Exceed Day 7 1 1 1 0  
   Normal Base; Exceed Day 28 0 1 0 0  
   Normal Day7; Exceed Day 28 0 0 1 2  
  LDH No Change 9 9 12 11 0.26
   Normal Base; Exceed Day 7 1 0 0 0  
   Normal Base; Exceed Day 28 0 0 0 2  
   Normal Day7; Exceed Day 28 1 2 1 0  
Creatine No Change 7 7 10 11 0.75
Kinase Normal Base; Exceed Day 7 2 1 1 0  
   Normal Base; Exceed Day 28 0 0 0 0  
   Normal Day7, Exceed Day 28 2 3 2 2  
Muscle Creatinine No Change 11 9 11 11 0.32
  Normal Base; Exceed Day 7 0 0 0 0  
  Normal Base; Exceed Day 28 0 1 0 2  
  Normal Day7; Exceed Day 28 0 1 2 0  
Kidney BUN No Change 10 8 11 12 0.37
  Normal Base; Exceed Day 7 0 0 1 0  
  Normal Base; Exceed Day 28 0 2 0 0  
   Normal Day7; Exceed Day 28 1 1 1 1  
  ALP No Change 11 11 13 13 0.32
   Normal Base; Exceed Day 7 0 0 0 0  
   Normal Base; Exceed Day 28 0 0 0 0  
   Normal Day7; Exceed Day 28 0 0 0 0  
Liver ALT No Change 11 9 12 11 0.49
  Normal Base; Exceed Day 7 0 0 0 0  
  Normal Base; Exceed Day 28 0 2 1 2  
  Normal Day7; Exceed Day 28 0 0 0 0  
AST No Change 8 8 12 8 0.54
   Normal Base; Exceed Day 7 1 0 1 0  
   Normal Base; Exceed Day 28 1 1 0 2  
   Normal Day7; Exceed Day 28 1 2 0 3  
  1. Data are presented as frequency. Statistical significance is detailed from chi-square analyses