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Table 2 Anthropometry and blood lipid, glucose, nitrate, and creatine characteristics of Study 2 participants

From: Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance

   Day   
Variable Group Baseline 7 28   p-level
Body Weight PLA 77.3 ± 11.9 77.6 ± 12.1 77.4 ± 12.7 Group 0.003
(kg) CrM 81.7 ± 13.2 82.4 ± 13.4 82.6 ± 14.0 Time 0.002
  CrN-Low 72.0 ± 9.7 72.2 ± 9.9 72.7 ± 10.0 Group × Time 0.29
  CrN-High 90.8 ± 13.4 90.8 ± 13.2 92.0 ± 14.3   
Fat Mass PLA 12.7 ± 6.3 12.6 ± 6.3 12.7 ± 6.3 Group 0.02
(kg) CrM 12.9 ± 5.3 13.0 ± 5.5 13.2 ± 5.2 Time 0.17
  CrN-Low 8.9 ± 4.7 8.7 ± 4.6 9.1 ± 4.7 Group × Time 0.90
  CrN-High 16.5 ± 6.9 16.2 ± 6.4 16.6 ± 7.4   
Fat-Free Mass PLA 58.1 ± 8.0 58.5 ± 8.0 58.3 ± 8.3 Group 0.01
(kg) CrM 62.4 ± 8.7 62.5 ± 8.8 62.9 ± 9.2 Time 0.02
  CrN-Low 56.9 ± 7.4 57.4 ± 7.3 57.3 ± 7.3 Group × Time 0.50
  CrN-High 67.4 ± 8.1 67.7 ± 8.2 68.5 ± 8.2   
Body Fat PLA 17.8 ± 6.9 17.1 ± 6.7 17.2 ± 6.7 Group 0.07
(%) CrM 16.7 ± 4.0 16.8 ± 4.3 16.8 ± 3.7 Time 0.24
  CrN-Low 13.1 ± 5.4 12.8 ± 5.2 13.2 ± 5.2 Group × Time 0.78
  CrN-High 19.2 ± 5.9 18.7 ± 5.5 18.8 ± 6.3   
Total Body Water PLA 51.3 ± 4.5 50.6 ± 5.1 52.5 ± 6.9 Group 0.18
(%) CrM 51.4 ± 3.3 50.8 ± 3.7 49.4 ± 8.4 Time 0.64
  CrN-Low 52.9 ± 4.6 54.1 ± 5.1 52.7 ± 4.2 Group × Time 0.47
  CrN-High 50.6 ± 6.5 48.8 ± 4.1 49.0 ± 4.7   
Lipids, Glucose, Nitrate, and Creatine   
 Total-C PLA 165.0 ± 33.4 161.5 ± 38.8 164.6 ± 38.8 Group 0.19
 (mg/dl) CrM 174.4 ± 25.5 175.4 ± 27.8 183.4 ± 41.1 Time 0.38
  CrN-Low 151.9 ± 35.8 149.7 ± 29.5 150.0 ± 37.5 Group × Time 0.83
  CrN-High 162.7 ± 25.1 155.9 ± 23.8 160.7 ± 29.1   
 HDL-C PLA 49.2 ± 11.4 50.6 ± 10.2 50.3 ± 12.8 Group 0.62
 (mg/dl) CrM 51.8 ± 15.2 54.7 ± 15.5 55.2 ± 17.4 Time 0.36
  CrN-Low 48.6 ± 15.7 48.3 ± 15.1 47.9 ± 12.8 Group × Time 0.85
  CrN-High 46.7 ± 10.7 47.2 ± 12.3 48.7 ± 10.6   
 Total-C/HDL-C PL 3.45 ± 0.71 3.23 ± 0.64 3.30 ± 0.59 Group 0.82
 Ratio CrM 3.70 ± 1.46 3.50 ± 1.34 3.69 ± 1.58 Time 0.24
 (mg/dl) CrN-Low 3.26 ± 0.81 3.32 ± 1.04 3.29 ± 1.05 Group × Time 0.74
  CrN-High 3.62 ± 0.82 3.47 ± 0.88 3.44 ± 0.94   
 LDL-C PLA 93.4 ± 23.4 91.7 ± 29.6 95.8 ± 34.6 Group 0.34
 (mg/dl) CrM 103.8 ± 33.3 106.6 ± 33.5 112.2 ± 49.0 Time 0.36
  CrN-Low 86.3 ± 22.6 84.8 ± 23.7 87.3 ± 28.7 Group × Time 0.88
  CrN-High 95.2 ± 25.0 93.4 ± 22.9 94.3 ± 28.4   
 Triglyceride PLA 109.1 ± 52.5 98.2 ± 36.9 94.2 ± 19.1 Group 0.63
 (mg/dl) CrM 114.5 ± 60.6 93.1 ± 30.9 112.0 ± 42.6 Time 0.16
  CrN-Low 87.5 ± 43.2 90.7 ± 49.1 85.8 ± 30.7 Group × Time 0.69
  CrN-High 104.8 ± 47.1 85.6 ± 39.2 97.2 ± 49.8   
 Glucose PLA 102.0 ± 18.6 102.1 ± 15.3 94.9 ± 12.6 Group 0.74
 (mg/dl) CrM 97.5 ± 13.9 99.7 ± 15.1 100.4 ± 16.8 Time 0.70
  CrN-Low 96.1 ± 8.5 96.1 ± 7.9 96.4 ± 17.9 Group × Time 0.27
  CrN-High 97.1 ± 9.4 93.2 ± 5.2 96.0 ± 9.4   
 Nitrate PLA 4.5 ± 2.0 5.1 ± 3.3 9.0 ± 15.3 Group 0.001
 (μmol/L) CrM 4.9 ± 3.6 3.8 ± 1.8 4.5 ± 1.8 Time 0.001
  CrN-Low 5.6 ± 3.1 64.8 ± 30.9a,b 13.9 ± 13.9 Group × Time 0.001
  CrN-High 4.3 ± 1.6 72.0 ± 47.3a,b 21.5 ± 28.9b   
 Creatine PLA 131.1 ± 92.2 143.5 ± 131.9 150.6 ± 152.0 Group 0.04
 (μmol/L) CrM 165.2 ± 94.4c 504.9 ± 422.8d 231.2 ± 126.1 Time 0.001
  CrN-Low 73.0 ± 56.4 170.4 ± 153.7 147.9 ± 95.3 Group × Time 0.01
  CrN-High 120.3 ± 99.8 241.3 ± 131.9 251.9 ± 406.4   
  1. Data are mean ± SD. To convert respective values to mmol/L multiply total cholesterol, HDL-C and LDL-C multiply by 0.0259; triglycerides by 0.0113, BUN by 0.357 and glucose by 0.0555. To convert creatinine to μmol/L multiply by 88.54. p < 0.05 considered significant
  2. Statistical notations. adenotes a significant difference from PLA. bdenotes a significant difference from CrM. cdenotes a significant difference from CrN-Low. ddenotes a significant difference from PLA, CrN-Low, and CrN-High