Fig. 4

Plasma creatine kinase (CK) measured in the morning at Day 1, 3, 5, 6, and 7. a Mean values of CK in the two groups (means ± SE); b Individual changes in CK in each group. # p < 0.05: Significant difference between groups (PRO-CHO vs. CHO) at baseline at D1. * p < 0.05: Significant difference from D1 in the PRO-CHO group. $ p < 0.01: Overall significant interaction between time and treatment effect