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Table 11 Markers of catabolism and bone status

From: A buffered form of creatine does not promote greater changes in muscle creatine content, body composition, or training adaptations than creatine monohydrate

Marker

N

Group

Day

 

p-level

   

0

7

28

  

BUN (mg/dl)

11

KA-L

16.0 ± 5.3

15.3 ± 4.9

15.6 ± 5.1

Group

0.89

 

12

KA-H

16.1 ± 3.3

16.6 ± 3.9

16.6 ± 3.6

Time

0.70

 

12

CrM

16.4 ± 3.2

15.7 ± 2.7

16.1 ± 4.7

G x T

0.75

Creatinine

11

KA-L

1.04 ± 0.08

1.08 ± 0.11

1.13 ± 0.10†

Group

0.07

(mg/dl)

12

KA-H

1.07 ± 0.14

1.23 ± 0.18†*

1.26 ± 0.13†*

Time

0.001

 

12

CrM

1.11 ± 0.19

1.28 ± 0.20†*

1.23 ± 0.15†*

G x T

0.03

BUN:CRN Ratio

11

KA-L

15.5 ± 5.1

14.5 ± 5.6

14.1 ± 5.6

Group

0.83

 

12

KA-H

15.1 ± 3.4

13.7 ± 3.4

13.3 ± 3.4

Time

0.001

 

12

CrM

15.2 ± 3.7

12.4 ± 2.6

13.2 ± 3.8

G x T

0.24

AST (U/L)

11

KA-L

25.4 ± 9.6

26.5 ± 8.4

29.5 ± 12.9

Group

0.62

 

12

KA-H

27.3 ± 10.5

25.6 ± 8.3

32.0 ± 12.0

Time

0.02

 

12

CrM

24.9 ± 7.9

23.8 ± 7.5

26.3 ± 7.8

G x T

0.70

ALT (U/L)

11

KA-L

21.5 ± 11.2

23.5 ± 14.2

28.7 ± 19.4

Group

0.50

 

12

KA-H

24.1 ± 15.6

22.3 ± 12.2

27.3 ± 9.1

Time

0.05

 

12

CrM

21.3 ± 7.34

18.0 ± 4.2

21.3 ± 5.5

G x T

0.48

Total Protein (g/dl)

11

KA-L

7.4 ± 0.6

7.4 ± 0.4

7.4 ± 0.4

Group

0.87

 

12

KA-H

7.3 ± 0.3

7.3 ± 0.3

7.3 ± 0.2

Time

0.88

 

12

CrM

7.3 ± 0.2

7.3 ± 0.2

7.4 ± 0.3

G x T

0.84

TBIL (mg/dl)

11

KA-L

0.84 ± 0.7

0.75 ± 0.3

0.76 ± 0.3

Group

0.60

 

12

KA-H

0.88 ± 0.5

0.89 ± 0.5

0.77 ± 0.4

Time

0.90

 

12

CrM

0.63 ± 0.2

0.71 ± 0.2

0.77 ± 0.2

G x T

0.26

Bone Mineral

11

KA-L

2,517 ± 404

2,503 ± 409

2,505 ± 398

Group

0.59

Content (g)

12

KA-H

2,632 ± 457

2,604 ± 466

2,615 ± 456

Time

0.49

 

12

CrM

2,446 ± 344

2,456 ± 0.2

2,441 ± 351

G x T

0.66

Albumin (g/dl)

11

KA-L

4.80 ± 0.3

4.81 ± 0.4

4.81 ± 0.2

Group

0.95

 

12

KA-H

4.83 ± 0.2

4.74 ± 0.2

4.78 ± 0.1

Time

0.73

 

12

CrM

4.82 ± 0.2

4.80 ± 364

4.79 ± 0.2

G x T

0.89

Globulin (g/dl)

11

KA-L

2.60 ± 0.4

2.63 ± 0.3

2.55 ± 0.3

Group

0.90

 

12

KA-H

2.56 ± 0.3

2.58 ± 0.2

2.52 ± 0.3

Time

0.85

 

12

CrM

2.55 ± 0.3

2.54 ± 0.2

2.62 ± 0.3

G x T

0.42

Alb:Glob Ratio

11

KA-L

1.88 ± 0.3

1.85 ± 0.2

1.90 ± 0.2

Group

0.98

 

12

KA-H

1.90 ± 0.1

1.86 ± 0.2

1.91 ± 0.1

Time

0.70

 

12

CrM

1.88 ± 0.2

1.90 ± 0.2

1.84 ± 0.2

G x T

0.45

Calcium (mg/dl)

11

KA-L

9.87 ± 0.5

9.85 ± 0.5

9.76 ± 0.4

Group

0.42

 

12

KA-H

9.83 ± 0.2

9.81 ± 0.4

9.84 ± 0.2

Time

0.51

 

12

CrM

9.77 ± 0.3

9.63 ± 0.4

9.67 ± 0.3

G x T

0.76

ALK (U/L)

11

KA-L

82.0 ± 16.4

84.1 ± 20.5

83.9 ± 17.0

Group

0.88

 

12

KA-H

81.1 ± 29.7

83.8 ± 30.3

87.1 ± 27.6

Time

0.29

 

12

CrM

78.9 ± 20.7

80.6 ± 26.4

78.8 ± 23.1

G x T

0.65

  1. Values are means ± standard deviations. Data were analyzed by MANOVA with repeated measures. Greenhouse-Geisser time and group x time (G x T) interaction p-levels are reported with univariate group p-levels. † represents p < 0.05 difference from baseline. * represents p < 0.05 difference from KA-L.
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Journal of the International Society of Sports Nutrition

ISSN: 1550-2783

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