Effects of diet type and supplementation of glucosamine, chondroitin, and MSM on body composition, functional status, and markers of health in women with knee osteoarthritis initiating a resistance-based exercise and weight loss program

Magrans-Courtney, Teresa; Wilborn, Colin; Rasmussen, Christopher; Ferreira, Maria; Greenwood, Lori; Campbell, Bill; Kerksick, Chad M; Nassar, Erica; Li, Rui; Iosia, Mike; Cooke, Matt; Dugan, Kristin; Willoughby, Darryn; Soliah, LuAnn; Kreider, Richard B

doi:10.1186/1550-2783-8-8

Journal of the International Society of Sports Nutrition

Table 5 Mean isokinetic knee extension and flexion data observed over time

From: Effects of diet type and supplementation of glucosamine, chondroitin, and MSM on body composition, functional status, and markers of health in women with knee osteoarthritis initiating a resistance-based exercise and weight loss program

Variable	0	Weeks 10	14	Group	p-level Time	G × T
*5 Repetitions at 60 deg/sec*
Peak Torque - RL Extension (kg/m)	9.90 ± 2.0	10.38 ± 2.6	10.69 ± 2.8	0.36	0.13	0.69
Peak Torque - LL Extension (kg/m)	9.15 ± 2.2	10.38 ± 2.6†	10.34 ± 2.9†	0.47	0.04	0.44
Peak Torque - RL Flexion (kg/m)	4.66 ± 1.6	5.53 ± 1.6†	5.99 ± 2.1†	0.62	0.003	0.90
Peak Torque - LL Flexion (kg/m)	4.44 ± 1.6	5.47 ± 1.7†	5.61 ± 1.9†	0.71	0.01	0. 45
Fatigue Index - RL Extension (%)	-0.8 ± 50	9.4 ± 18	8.7 ± 25	0.79	0.32	0.54
Fatigue Index - LL Extension (%)	3.5 ± 30	11.1 ± 19	11.0 ± 18	0.73	0.38	0.41
Fatigue Index - RL Flexion (%)	-8.8 ± 72	16.9 ± 28†	25.3 ± 13†	0.23	0.02	0.28
Fatigue Index - LL Flexion (%)	12.6 ± 30	19.4 ± 18	23.4 ± 10	0.82	0.12	0.75
*10 Repetitions at 180 deg/sec*
Peak Torque - RL Extension (kg/m)	6.05 ± 2.3	6.45 ± 2.4	6.82 ± 2.4†	0.12	0.05	0.40
Peak Torque - LL Extension (kg/m)	5.60 ± 2.8	6.40 ± 2.7	6.85 ± 2.3†	0.47	0.04	0.44
Peak Torque - RL Flexion (kg/m)	2.80 ± 1.5	3.70 ± 1.8†	4.10 ± 1.9†	0.35	0.001	0.66
Peak Torque - LL Flexion (kg/m)	2.68 ± 1.7	3.49 ± 1.6†	3.90 ± 1.7†	0.60	0.001	0. 48
Fatigue Index - RL Extension (%)	-1.9 ± 33	-9.6 ± 67	9.5 ± 26	0.19	0.12	0.84
Fatigue Index - LL Extension (%)	-17.6 ± 55	5.2 ± 27†	-0.2 ± 47†	0.08	0.02	0.49
Fatigue Index - RL Flexion (%)	-12.1 ± 84	7.9 ± 56†	17.7 ± 22†	0.37	0.08	0.53
Fatigue Index - LL Flexion (%)	-48.9 ± 139	9.8 ± 53†	9.7 ± 67†	0.61	0.02	0.44
*15 Repetitions at 300 deg/sec*
Peak Torque - RL Extension (kg/m)	32.6 ± 13	36.6 ± 14	36.2 ± 15	0.68	0.17	0.39
Peak Torque - LL Extension (kg/m)	31.0 ± 16	36.2 ± 15†	37.0 ± 15†	0.62	0.02	0.12
Peak Torque - RL Flexion (kg/m)	14.8 ± 11	19.0 ± 13†	19.3 ± 13†	0.76	0.02	0.61
Peak Torque - LL Flexion (kg/m)	12.7 ± 11	17.2 ± 12†	17.6 ± 11†	0.82	0.02	0. 24
Fatigue Index - RL Extension (%)	7.8 ± 43	10.8 ± 27	17.2 ± 29	0.46	0.19	0.83
Fatigue Index - LL Extension (%)	4.0 ± 48	11.3 ± 24	17.6 ± 37	0.46	0.25	0.77
Fatigue Index - RL Flexion (%)	-2.0 ± 94	14.1 ± 70	17.9 ± 68†	0.52	0.36	0.82
Fatigue Index - LL Flexion (%)	-20.2 ± 103	16.3 ± 89†	19.1 ± 62†	0.76	0.02	0.94

Data are means ± standard deviations for time main effects. RL = right leg, LL = left leg, G = group, T = time. † Indicates p < 0.05 difference from baseline.

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ISSN: 1550-2783

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