Skip to main content

Table 1 Studies investigating the effects of BCAA supplementation of RE-based muscle damage in humans

From: Potential therapeutic effects of branched-chain amino acids supplementation on resistance exercise-based muscle damage in humans

Study Exercise Protocol Supplementation Protocol Results
Shimomura et al. [29] Squat (7 sets of 20 repetitions) 5.5 g of BCAA within 1.0 g of green tea 15 min before exercise Attenuation of exercise-induced serum BCAA oxidation.
Shimomura et al. [30] Squat (7 sets of 20 repetitions) 5.0 g of BCAA 15 min before exercise Reduction of peak time of muscle soreness induced by exercise.
Nosaka et al.[3] 900 actions (30 min) of arm curl with 1.80 to 3.44 kg of range of workload BCAA-enriched amino acid mixture (60% of the essential amino acids) Reduction of serum CK, myoglobin, and muscle soreness. No differences in isometric MVC.
Sharp & Pearson [31] Whole body RE (3 sets of 8 RM, 8 exercises) BCAA (1.8 g of leucine, 0.75 g of isoleucine, and 0.75 g of valine) 3 weeks before and 1 week during exercise protocol Reduction of serum CK.
Jackman et al. [32] Eccentric exercise (12 sets of 10 repetitions at 120% of concentric 1RM) ~ 7.0 g of BCAA/day (divided in 4 doses) on the following 2 days after exercise No differences in serum CK and myoglobin; Attenuation in exercise-induced muscle soreness.
  1. BCAA = branched-chain amino acids; CK = creatine kinase; MVC = maximal voluntary contraction; RE = resistance exercise; RM = repetition maximum.