Skip to main content

Table 4 Phosphorylated levels of Akt/mTOR pathway intermediates for WP and CHO.

From: Ingestion of 10 grams of whey protein prior to a single bout of resistance exercise does not augment Akt/mTOR pathway signaling compared to carbohydrate

Variable

Time Point

WP

CHO

p-value

IRS-1

Baseline

15.68 ± 9.6

19.52 ± 6.4

Supplement (S) = 0.88

 

15 min post-exercise

29.04 ± 6.6†

22.28 ± 11.2

Test (T) = 0.04†#

 

120 min post-exercise

25.40 ± 6.0

19.65 ± 9.2

S × T = 0.44

Akt

Baseline

5.04 ± 1.9

6.88 ± 1.1

Supplement (S) = 0.21

 

15 min post-exercise

6.04 ± 2.6

5.61 ± 4.1

Test (T) = 0.35

 

120 min post-exercise

4.78 ± 1.4

4.58 ± 2.1

S × T = 0.82

mTOR

Baseline

3.34 ± 0.34

3.62 ± 0.19

Supplement (S) = 0.93

 

15 min post-exercise

3.75 ± 0.62

3.66 ± 0.27

Test (T) = 0.002†

 

120 min post-exercise

3.33 ± 0.19

3.52 ± 0.28

S × T = 0.34

P70S6K

Baseline

8.51 ± 3.2

10.41 ± 3.2

Supplement (S) = 0.96

 

15 min post-exercise

14.14 ± 6.6

11.18 ± 2.9

Test (T) = 0.04

 

120 min post-exercise

13.32 ± 6.1

11.24 ± 5.0

S × T = 0.74

4E-BP1

Baseline

4.30 ± 2.4

5.33 ± 1.7

Supplement (S) = 0.28

 

15 min post-exercise

2.66 ± 1.3†

2.28 ± 1.0

Test (T) = 0.001†

 

120 min post-exercise

4.07 ± 1.9#

4.90 ± 1.8

S × T = 0.64

  1. Data are means ± standard deviations.
  2. p70S6K, eIF4E-BP1, AKT and IRS-1 are expressed as U/ml/mg.
  3. mTOR is expressed as absorbance units at 450 nm/mg.
  4. † represents significant difference from baseline at 15 min post-exercise.
  5. # represents significant difference from baseline at 120 min post-exercise.