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Table 3 Total Trp:LNAA, total Trp:Tyr, free-Trp:LNAA and free-Trp:Tyr ratios before and after supplementation.

From: Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation

    Blood collection time (min)
  Group Trial Rest 40 End
Total [Trp]:[LNAA] ratio Plc Pre .069(.016) .071(.015) .076(.016)
   Post .070(.012) .072(.017) .084(.022)
  Cr Pre .062(.013) .069(.010) .075(.012)
   Post .073(.016) .080(.016) .082(.007)§
  Resp Pre .062(.012) .069(.010) .076(.014)
   Post .076(.016) .077(.019) .082(.006)§
Total [Trp]:[Tyr] ratio Plc Pre 0.65(.24) 0.61(.09) 0.58(.17)
   Post 0.71(.07) 0.68(.18) 0.74(.19)
  Cr Pre 0.64(.14) 0.63(.07) 0.61(.15)
   Post 0.65(.16) 0.62(.14) 0.65(.09)
  Resp Pre 0.66(.20) 0.62(.09) 0.61(.17)
   Post 0.71(.16) 0.62(.20) 0.62(.09)
Free-[Trp]:[LNAA] ratio Plc Pre .0030(.0007) .0040(.0010) .0036(.0020)
   Post .0031(.0024) .0038(.0014) .0048(.0012)
  Cr Pre .0034(.0021) .0032(.0015) .0037(.0016)
   Post .0028(.0015) .0038(.0017) .0028(.0027)
  Resp Pre .0042(.0020) .0034(.0010) .0045(.0012)
   Post .0027(.0015) .0039(.0017) .0043(.0025)
Free-[Trp]:[Tyr] ratio Plc Pre .032(.017) .035(.008) .027(.014)
   Post .035(.018) .039(.012) .043(.013)
  Cr Pre .034(.027) .032(.013) .027(.012)
   Post .028(.016) .028(.013) .024(.019)
  Resp Pre .042(.025) .033(.011) .032(.013)
   Post .032(.017)* .026(.015)*§ .029(.018)
  1. Values are given as median (IQR).
  2. * Indicates a significant difference from pre-supplementation values
  3. § Indicates a significant difference over time compared with the resting value
  4. Resp: "responders"