Controversies of antioxidant vitamins supplementation in exercise: ergogenic or ergolytic effects in humans?

Table 2 Results of the studies with untrained volunteers submitted to endurance exercise and supplemented with vitamins C e E

Study	Experimental design	Sample	Duration	Supplementation protocol		Result
				Vitamin C	Vitamin E	Ergogenic	Ergolytic
Bloomer et al. [13]	Randomized, double-blind	15 trained and e 15 untrained subjects	14 d (pre-exercise) + 2 d (post-exercise)	2000 mg	835 mg	↔	↔
Gomez-Cabrera et al. [7]	Randomized, double-blind	14 untrained subjects e 36 rats	8 weeks	1 g (humans) and 0.24 mg∙cm^-2 (rodents)	-	N/R	↓
Ristow et al. [3]	Randomized, double-blind	20 trained and e 20 untrained subjects	4 weeks	1000 mg	440 mg	N/R	↓
Yfanti et al. [14]	Randomized, double-blind	21 untrained subjects	16 weeks	500 mg	400 IU	↔	↔
Yfanti et al. [5]	Randomized, double-blind	21 untrained subjects	16 weeks	500 mg	400 IU	↔	↔
Nalbant et al. [8]	Randomized	57 elderly	6 months		900 IU	↔	↔
Nakhostin et al. [15]	Randomized	16 untrained subjects	N/R	1000 mg	-	↑↓	N/R

↑ Improved exercise performance; ↓ Impaired exercise performance; ↑↓ Partial result; ↔ No results on exercise performance; IU – International Units; N/R – not reported.

ISSN: 1550-2783