The effects of a multi-ingredient dietary supplement on body composition, adipokines, blood lipids, and metabolic health in overweight and obese men and women: a randomized controlled trial

Table 5 Endocrine changes at week 0 and week 8

Variables	Group	n	Pre	Post	∆	Time p	Time × group p
Insulin (μIU/mL)	PL	11	18.8 ± 3.6	17.2 ± 1.5	−1.6	0.57	0.16
Insulin (μIU/mL)	MIDS	10	11.4 ± 1.2	15.1 ± 2.0	+3.7	0.57	0.16
Leptin (pg/mL)	PL	11	52.2 ± 11.4	42.0 ± 8.1	−10.2	0.13	0.58
Leptin (pg/mL)	MIDS	11	30.7 ± 7.6	25.9 ± 7.5	−4.8	0.13	0.58
Adiponectin (μg/mL)	PL	11	5.9 ± 0.8	6.5 ± 1.2	+0.6	0.73	0.12
Adiponectin (μg/mL)	MIDS	11	9.8 ± 1.7	8.9 ± 1.5	−0.9	0.73	0.12
hs – CRP (mg/L)	PL	11	4.4 ± 1.1	4.6 ± 1.3	+0.2	0.89	0.37
hs – CRP (mg/L)	MIDS	10	2.8 ± 0.9	2.5 ± 0.6	−0.3	0.89	0.37
Glucose (mg/dl)	PL	11	99.0 ± 3.3	98.2 ± 4.4	- 0.8	0.94	0.78
Glucose (mg/dl)	MIDS	11	96.3 ± 4.3	96.9 ± 5.0	+0.6	0.94	0.78
HOMA-IR	PL	11	4.66 ± 0.98	4.19 ± 0.42	−0.47	0.73	0.19
HOMA-IR	MIDS	10	2.82 ± 0.44	3.61 ± 0.52	+0.81	0.73	0.19
A/L	PL	11	0.36 ± 0.1	0.44 ± 0.1	+0.08	0.13	0.39
A/L	MIDS	11	1.1 ± 0.2	1.3 ± 0.23	+0.2	0.13	0.39

Data are mean ± SEM; PL, Placebo; MIDS, multi-ingredient dietary supplement; hs-CRP, high sensitivity C reactive protein; HOMA-IR, homeostatic model assessment insulin resistance; A, Adiponectin; L, Leptin; n is different for insulin and hs-CRP as data was missing due to technical errors.
∆ change from week 0 to week 8.

ISSN: 1550-2783