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Table 5 Endocrine changes at week 0 and week 8

From: The effects of a multi-ingredient dietary supplement on body composition, adipokines, blood lipids, and metabolic health in overweight and obese men and women: a randomized controlled trial

Variables Group n Pre Post Time p Time × group p
Insulin (μIU/mL) PL 11 18.8 ± 3.6 17.2 ± 1.5 −1.6 0.57 0.16
MIDS 10 11.4 ± 1.2 15.1 ± 2.0 +3.7
Leptin (pg/mL) PL 11 52.2 ± 11.4 42.0 ± 8.1 −10.2 0.13 0.58
MIDS 11 30.7 ± 7.6 25.9 ± 7.5 −4.8
Adiponectin (μg/mL) PL 11 5.9 ± 0.8 6.5 ± 1.2 +0.6 0.73 0.12
MIDS 11 9.8 ± 1.7 8.9 ± 1.5 −0.9
hs – CRP (mg/L) PL 11 4.4 ± 1.1 4.6 ± 1.3 +0.2 0.89 0.37
MIDS 10 2.8 ± 0.9 2.5 ± 0.6 −0.3
Glucose (mg/dl) PL 11 99.0 ± 3.3 98.2 ± 4.4 - 0.8 0.94 0.78
MIDS 11 96.3 ± 4.3 96.9 ± 5.0 +0.6
HOMA-IR PL 11 4.66 ± 0.98 4.19 ± 0.42 −0.47 0.73 0.19
MIDS 10 2.82 ± 0.44 3.61 ± 0.52 +0.81
A/L PL 11 0.36 ± 0.1 0.44 ± 0.1 +0.08 0.13 0.39
MIDS 11 1.1 ± 0.2 1.3 ± 0.23 +0.2
  1. Data are mean ± SEM; PL, Placebo; MIDS, multi-ingredient dietary supplement; hs-CRP, high sensitivity C reactive protein; HOMA-IR, homeostatic model assessment insulin resistance; A, Adiponectin; L, Leptin; n is different for insulin and hs-CRP as data was missing due to technical errors.
  2. ∆ change from week 0 to week 8.