Figure 1

Effect of quercetin and exercise on atherosclerotic lesion development. A: Images of the atherosclerotic lesions in aortas. Atherosclerotic lesions in aortas of LDLr−/−mice fed a high-fat diet. NN: Control group; mice on atherogenic diet without quercetin and exercise treatment; EN: Mice on atherogenic diet and exercise without quercetin supplementation; NQ: Mice on atherogenic diet and quercetin supplementation; EQ: Mice on atherogenic diet, exercise and quercetin supplementation. Massive formation of atherosclerotic plaque can be seen on control and relatively less lesion formation on the other groups. B: Lesions areas dot plot representation in the 4 groups. EN: Mice on atherogenic diet and exercise without quercetin intake NQ: Mice on atherogenic diet and quercetin intake. EQ: Mice on atherogenic diet and exercise and quercetin intake. Compared to NN mice; the aorta lesion areas in EN, NQ and EQ showed significant decreases of 79%, 64% and 70% respectively (P < 0.05).