Skip to main content

Table 7 Clinical whole blood safety markers, part I

From: Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use

Variable

T1

T2

T3

Time*group

Time*group*gender

White blood cells (103 cells/μL)

 PLA

6.0 ± 1.8

5.9 ± 1.7

6.2 ± 1.6

Time p = 0.52

G*T*Ge p = 0.18

 LD

6.5 ± 1.5

6.3 ± 1.5

6.4 ± 1.5

G*T p = 0.52

 HD

6.9 ± 1.5

6.5 ± 1.2

6.4 ± 1.8

RBC (106 cells/μl)

 PLA

4.4 ± 0.4

4.4 ± 0.5

4.5 ± 0.4

Time p = 0.12

G*T*Ge p = 0.10

 LD

4.8 ± 0.4

4.7 ± 0.4

4.8 ± 0.4

G*T p = 0.36

 HD

4.8 ± 0.4

4.8 ± 0.5

4.8 ± 0.5

Hemoglobin (g/dL)

 PLA

13.8 ± 1.0

13.7 ± 1.5

13.9 ± 1.3 ‡

Time p = 0.56

G*T*Ge p  = 0.006

 LD

14.4 ± 1.1

14.3 ± 1.1

14.5 ± 1.1

G*T p = 0.78

 HD

14.2 ± 1.4

14.1 ± 1.3

14.1 ± 1.4

Hematocrit (%)

 PLA

41 ± 3

41 ± 5

42 ± 3 ‡

Time p = 0.23

G*T*Ge p  = 0.049

 LD

43 ± 4

43 ± 3

44 ± 3

G*T p = 0.85

 HD

43 ± 4

43 ± 4

43 ± 4

Platelet Count (103 particles/μL)

 PLA

160 ± 46

191 ± 50 †

204 ± 89

Time p  = 0.005

G*T*Ge p = 0.16

 LD

148 ± 61

176 ± 35

212 ± 71

G*T p = 0.77

 HD

191 ± 40

216 ± 51

227 ± 41

Neutrophils (103 cells/μL)

 PLA

3123 ± 843

3441 ± 1440

3679 ± 1443

Time p = 0.67

G*T*Ge p = 0.12

 LD

3423 ± 920

3196 ± 862

3444 ± 881

G*T p = 0.28

 HD

3631 ± 1417

3570 ± 921

3452 ± 1423

Lymphocytes (103 cells/μL)

 PLA

1881 ± 543

1908 ± 479

1928 ± 492

Time p = 0.20

G*T*Ge p = 0.50

 LD

2393 ± 698

2325 ± 738

2232 ± 681

G*T p = 0.13

 HD

2624 ± 664

2200 ± 425

2384 ± 761

Monocytes (103 cells/μL)

 PLA

426 ± 123

414 ± 150

412 ± 131

Time p = 0.97

G*T*Ge p = 0.07

 LD

467 ± 149

498 ± 131

456 ± 156

G*T p = 0.65

 HD

424 ± 184

399 ± 106

427 ± 123

Eosinophils (103 cells/μL)

 PLA

157 ± 109

187 ± 125 †

166 ± 115

Time p = 0.62

G*T*Ge p  = 0.002

 LD

187 ± 108

187 ± 102

189 ± 112

G*T p  = 0.041

 HD

225 ± 130

164 ± 87

181 ± 83

Basophils (103 cells/μL)

 PLA

27 ± 12

24 ± 11

25 ± 12

Time p = 0.07

G*T*Ge p = 0.28

 LD

30 ± 14

36 ± 19

25 ± 11

G*T p = 0.21

 HD

32 ± 18

43 ± 23

33 ± 20

  1. Abbreviations: PLA Placebo, LD Theacrine Low Dose, HD Theacrine High Dose, G Group, T Time, Ge Gender
  2. Symbols: ‡, increase from corresponding T2 value within the female PLA group (p < 0.05); †, different from corresponding T1 value (p < 0.05). Items in bold indicate a significant effect (p < 0.05) was observed
Back to article page

Journal of the International Society of Sports Nutrition

ISSN: 1550-2783

Contact us