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Table 3 Mean (SD) peak plasma concentration (Crmax, mM), time to peak concentration (Tmax, h), area under the plasma concentration curve (AUC, mM.h), velocity constant of absorption (ka, h-1) and velocity constant of elimination (ke, h-1) following ingestion of isomolar amounts of creatine (4.4 g) in the form of creatine monohydrate (CrM), tri-creatine citrate (CrC), or creatine pyruvate (CrPyr). Means differing significantly are denoted by the letters a to c.

From: Comparison of new forms of creatine in raising plasma creatine levels

 

CrM (a)

CrC (b)

CrPyr (c)

ANOVA P value

 

Mean

SD

Mean

SD

Mean

SD

 

Crmax

751

32.9

837 c

71.5

968 a

82.3

0.008

T max

1.5 c

0.13

1.2

0.1

1.1 a

0.08

0.002

AUC

2384

376.5

2627

506.8

2985

540.6

0.023

ka

1.26

0.214

1.39

0.551

1.31

0.324

NS

kel

0.73

0.344

0.66

0.279

0.72

0.279

NS