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Table 2 Hemodynamic Safety Markers

From: Effects of eight weeks of an alleged aromatase inhibiting nutritional supplement 6-OXO (androst-4-ene-3,6,17-trione) on serum hormone profiles and clinical safety markers in resistance-trained, eugonadal males

 

300 mg

600 mg

Week

0

1

3

8

11

0

1

3

8

11

Heart Rate (bpm)

64 ± 7.6

58 ± 4.7

61 ± 5.1

61 ± 5.6

64 ± 8.7

57 ± 6.2

58 ± 6.7

59 ± 7.2

61 ± 3.0

64 ± 8.6

SBP (mmHg)

116 ± 13.0*

114 ± 9.8*

117 ± 12.3*

117 ± 10.7*

116 ± 8.8*

75 ± 8.7

74 ± 9.3

73 ± 8.1

70 ± 7.9

77 ± 5.6

BBP (mmHg)

109 ± 6.4

107 ± 5.2

113 ± 6.9

115 ± 11.4

114 ± 4.8

69 ± 8.2

74 ± 4.5

71 ± 9.4

76 ± 9.9

74 ± 6.3

  1. * Denotes significant main effects for groups (p < 0.05). Results indicated that the 300 mg group had significant higher baseline values that persisted throughout the study, and was apparently independent of 6-OXO supplementation.